Detailed information NTG0588149

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: KWY62_RS02535
• Genome accession: NZ_CP079193
• Coordinates: 495607..497835 (-)
• Length: 742 a.a.
• NCBI ID: WP_202847509.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ID41570
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 490607..502835

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KWY62_RS02515 (KWY62_02515)	-	491119..491562 (+)	444	WP_105153719.1	GNAT family N-acetyltransferase	-
KWY62_RS02520 (KWY62_02520)	ileS	491573..494362 (+)	2790	WP_172047356.1	isoleucine--tRNA ligase	-
KWY62_RS02525 (KWY62_02525)	-	494597..494905 (-)	309	WP_002938710.1	DUF1827 family protein	-
KWY62_RS02530 (KWY62_02530)	-	494960..495421 (-)	462	WP_002938708.1	NUDIX hydrolase	-
KWY62_RS02535 (KWY62_02535)	clpE	495607..497835 (-)	2229	WP_202847509.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
KWY62_RS02540 (KWY62_02540)	-	498059..498289 (+)	231	WP_002938704.1	DUF1797 family protein	-
KWY62_RS02545 (KWY62_02545)	-	498415..499104 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
KWY62_RS02550 (KWY62_02550)	-	499097..499831 (+)	735	WP_014637571.1	amino acid ABC transporter ATP-binding protein	-
KWY62_RS02555 (KWY62_02555)	-	500065..500913 (+)	849	WP_024380045.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82566.93 Da
• Isoelectric Point: 5.2782

>NTDB_id=588149 KWY62_RS02535 WP_202847509.1 495607..497835(-) (clpE) [Streptococcus suis strain ID41570]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKANIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=588149 KWY62_RS02535 WP_202847509.1 495607..497835(-) (clpE) [Streptococcus suis strain ID41570]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCTTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTCTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGACATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGACTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGACGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCGGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAGGAAATCGAAGCCATCGTAGAGCAAAAAGCAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAGGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGACATGTCCGAATATATGGAGAAACACGCCGTAGCCAAACTGGTCGGTGCCCCTCCAGGTTATG
TAGGCTACGAGGAAGCCGGTCAGCTAACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAAGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTGCGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

• AAA lid domain (AAA_lid_9) (291-389)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.228	100	0.836
clpE	Streptococcus pneumoniae D39	82.228	100	0.836
clpE	Streptococcus pneumoniae R6	82.228	100	0.836
clpE	Streptococcus pneumoniae TIGR4	82.228	100	0.836
clpE	Streptococcus mutans UA159	82.243	100	0.83
clpC	Lactococcus lactis subsp. cremoris KW2	77.517	97.709	0.757
clpC	Bacillus subtilis subsp. subtilis str. 168	52.308	87.601	0.458
clpC	Streptococcus mutans UA159	48.558	84.097	0.408
clpC	Streptococcus thermophilus LMD-9	48.248	84.636	0.408
clpC	Streptococcus thermophilus LMG 18311	47.93	84.636	0.406
clpC	Streptococcus pneumoniae Rx1	47.84	84.232	0.403
clpC	Streptococcus pneumoniae D39	47.84	84.232	0.403
clpC	Streptococcus pneumoniae TIGR4	47.84	84.232	0.403
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.656	84.636	0.395