Detailed information NTG0587772

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KVY05_RS18230
• Genome accession: NZ_CP079099
• Coordinates: 3618728..3619891 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain LBY-1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3613728..3624891

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KVY05_RS18200 (KVY05_18195)	-	3613992..3614411 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
KVY05_RS18205 (KVY05_18200)	comFC	3614485..3615174 (-)	690	WP_199022660.1	phosphoribosyltransferase family protein	Machinery gene
KVY05_RS18210 (KVY05_18205)	-	3615180..3615464 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
KVY05_RS18215 (KVY05_18210)	comFA	3615522..3616907 (-)	1386	WP_124692700.1	DEAD/DEAH box helicase	Machinery gene
KVY05_RS18220 (KVY05_18215)	-	3617016..3617864 (-)	849	WP_003151387.1	DegV family protein	-
KVY05_RS18225 (KVY05_18220)	degU	3617962..3618651 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KVY05_RS18230 (KVY05_18225)	degS	3618728..3619891 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KVY05_RS18235 (KVY05_18230)	-	3620114..3620761 (+)	648	WP_007614107.1	YigZ family protein	-
KVY05_RS18240 (KVY05_18235)	-	3620766..3621986 (+)	1221	WP_007407486.1	LCP family protein	-
KVY05_RS18245 (KVY05_18240)	-	3622085..3623161 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
KVY05_RS18250 (KVY05_18245)	-	3623294..3624490 (-)	1197	WP_218791395.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=587772 KVY05_RS18230 WP_007407484.1 3618728..3619891(-) (degS) [Bacillus velezensis strain LBY-1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=587772 KVY05_RS18230 WP_007407484.1 3618728..3619891(-) (degS) [Bacillus velezensis strain LBY-1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951