Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KVY09_RS04255 Genome accession   NZ_CP078159
Coordinates   874984..875700 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain NY5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 869984..880700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVY09_RS04235 (KVY09_04235) - 870024..871268 (+) 1245 WP_070440189.1 ammonium transporter -
  KVY09_RS04240 (KVY09_04240) - 871369..872328 (+) 960 WP_070440191.1 LacI family DNA-binding transcriptional regulator -
  KVY09_RS04245 (KVY09_04245) - 872413..873897 (+) 1485 WP_070440193.1 sucrose-6-phosphate hydrolase -
  KVY09_RS04250 (KVY09_04250) - 873901..874866 (+) 966 WP_070440195.1 carbohydrate kinase -
  KVY09_RS04255 (KVY09_04255) agrA 874984..875700 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  KVY09_RS04260 (KVY09_04260) agrC 875719..877002 (-) 1284 WP_070485438.1 quorum-sensing sensor histidine kinase AgrC -
  KVY09_RS04265 (KVY09_04265) agrD 877034..877171 (-) 138 WP_037551251.1 cyclic lactone autoinducer peptide AgrD -
  KVY09_RS04270 (KVY09_04270) - 877174..877740 (-) 567 WP_070440199.1 accessory gene regulator AgrB -
  KVY09_RS04275 (KVY09_04275) - 878469..879254 (-) 786 WP_070440201.1 carbon-nitrogen family hydrolase -
  KVY09_RS04280 (KVY09_04280) - 879447..880070 (-) 624 WP_070440204.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=587407 KVY09_RS04255 WP_011275301.1 874984..875700(-) (agrA) [Staphylococcus haemolyticus strain NY5]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=587407 KVY09_RS04255 WP_011275301.1 874984..875700(-) (agrA) [Staphylococcus haemolyticus strain NY5]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCT
ATTGGAAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCAATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACACACTCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAAACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGATTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAACAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCGGTTCGTAATGTTAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878