Detailed information NTG0586781

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: J5Y16_RS08950
• Genome accession: NZ_CP078097
• Coordinates: 1853452..1855644 (+)
• Length: 730 a.a.
• NCBI ID: WP_218209513.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei subsp. paracasei strain GR0548
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1848452..1860644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5Y16_RS08915 (J5Y16_08915)	-	1848546..1848719 (+)	174	WP_013246050.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
J5Y16_RS08920 (J5Y16_08920)	-	1848758..1848931 (+)	174	WP_013246049.1	bacteriocin	-
J5Y16_RS08925 (J5Y16_08925)	-	1849205..1849444 (-)	240	WP_218209511.1	hypothetical protein	-
J5Y16_RS08930 (J5Y16_08930)	-	1849991..1850188 (+)	198	WP_042753684.1	hypothetical protein	-
J5Y16_RS08935 (J5Y16_08935)	-	1850550..1851356 (-)	807	WP_218209512.1	LytTR family DNA-binding domain-containing protein	-
J5Y16_RS14535	-	1851361..1852658 (-)	1298	Protein_1740	GHKL domain-containing protein	-
J5Y16_RS08945 (J5Y16_08945)	-	1852848..1852985 (+)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
J5Y16_RS08950 (J5Y16_08950)	comA	1853452..1855644 (+)	2193	WP_218209513.1	peptide cleavage/export ABC transporter	Regulator
J5Y16_RS08955 (J5Y16_08955)	-	1855655..1857034 (+)	1380	WP_218209514.1	bacteriocin secretion accessory protein	-
J5Y16_RS08960 (J5Y16_08960)	-	1857208..1857558 (+)	351	WP_003567340.1	hypothetical protein	-
J5Y16_RS08965 (J5Y16_08965)	-	1857631..1857942 (+)	312	WP_003580849.1	hypothetical protein	-
J5Y16_RS08970 (J5Y16_08970)	-	1858248..1859603 (+)	1356	WP_003567335.1	threonine/serine exporter ThrE family protein	-
J5Y16_RS08975 (J5Y16_08975)	-	1859705..1860001 (+)	297	WP_003567333.1	bacteriocin immunity protein	-
J5Y16_RS08980 (J5Y16_08980)	-	1860194..1860478 (+)	285	WP_218209515.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81358.62 Da
• Isoelectric Point: 7.0227

>NTDB_id=586781 J5Y16_RS08950 WP_218209513.1 1853452..1855644(+) (comA) [Lacticaseibacillus paracasei subsp. paracasei strain GR0548]
MIKYNIKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPMLARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKVDQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHTELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=586781 J5Y16_RS08950 WP_218209513.1 1853452..1855644(+) (comA) [Lacticaseibacillus paracasei subsp. paracasei strain GR0548]
ATGATCAAATACAACATAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAATTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGAGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTCGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCACCAGAACCGCAATATCAACCACGCAAAGAGGAT
AAAGGCAGTCTTTTTGCGTTTGTGCCGATGCTGGCGCGGCAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTATT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACTTATTTGAAAAAGTCGTTCAATTATACAAAAGTTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTTACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGTGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCCATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCAATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATACTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• Peptidase C39 family (Peptidase_C39) (16-152)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.635	98.356	0.577
comA	Streptococcus pneumoniae Rx1	58.078	98.356	0.571
comA	Streptococcus pneumoniae D39	58.078	98.356	0.571
comA	Streptococcus pneumoniae R6	58.078	98.356	0.571
comA	Streptococcus mitis SK321	57.939	98.356	0.57
comA	Streptococcus pneumoniae TIGR4	57.66	98.356	0.567
comA	Streptococcus gordonii str. Challis substr. CH1	57.103	98.356	0.562
comA/nlmT	Streptococcus mutans UA159	54.986	98.904	0.544