Detailed information NTG0586265

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: KV238_RS06175
• Genome accession: NZ_CP078012
• Coordinates: 1272107..1273144 (+)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_18-036
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1267107..1278144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV238_RS06150 (KV238_06150)	-	1267419..1268750 (+)	1332	WP_230923386.1	dipeptidase	-
KV238_RS06155 (KV238_06155)	arcC	1268768..1269718 (+)	951	WP_043029469.1	carbamate kinase	-
KV238_RS06160 (KV238_06160)	asnA	1269938..1270930 (+)	993	WP_126436451.1	aspartate--ammonia ligase	-
KV238_RS06165 (KV238_06165)	rsmD	1271100..1271639 (+)	540	WP_012678322.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
KV238_RS06170 (KV238_06170)	coaD	1271629..1272129 (+)	501	WP_230923387.1	pantetheine-phosphate adenylyltransferase	-
KV238_RS06175 (KV238_06175)	sepM	1272107..1273144 (+)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
KV238_RS06180 (KV238_06180)	-	1273744..1274358 (+)	615	WP_115250705.1	YutD family protein	-
KV238_RS06185 (KV238_06185)	rlmN	1274362..1275444 (+)	1083	WP_012679163.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
KV238_RS06190 (KV238_06190)	-	1276033..1276911 (+)	879	WP_012678317.1	ABC transporter ATP-binding protein	-
KV238_RS06195	-	1276915..1277223 (+)	309	WP_230923388.1	hypothetical protein	-
KV238_RS06200	-	1277261..1277659 (+)	399	WP_230923389.1	ABC transporter permease	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=586265 KV238_RS06175 WP_014622492.1 1272107..1273144(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=586265 KV238_RS06175 WP_014622492.1 1272107..1273144(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTAGTGAGCCTCAGTCGGGCCACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGACTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTATCAGGCCCTTACTCTAGCAGGCAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701