Detailed information NTG0585553

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU512_RS11055
• Genome accession: NZ_CP077933
• Coordinates: 2150015..2150902 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 359
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2145015..2155902

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU512_RS11025 (KU512_11015)	-	2145034..2145126 (+)	93	WP_010956583.1	hypothetical protein	-
KU512_RS11030 (KU512_11020)	-	2145234..2145731 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU512_RS11035 (KU512_11025)	-	2145741..2146001 (-)	261	WP_001789910.1	hypothetical protein	-
KU512_RS11040 (KU512_11030)	-	2146383..2146496 (-)	114	WP_011447078.1	hypothetical protein	-
KU512_RS11045 (KU512_11035)	-	2147155..2149155 (-)	2001	WP_000776751.1	ABC transporter permease	-
KU512_RS11050 (KU512_11040)	-	2149152..2149907 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU512_RS11055 (KU512_11045)	braS	2150015..2150902 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU512_RS11060 (KU512_11050)	braR	2150913..2151578 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU512_RS11065 (KU512_11055)	-	2151604..2151804 (-)	201	WP_000604728.1	hypothetical protein	-
KU512_RS11070 (KU512_11060)	-	2152002..2153426 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KU512_RS14560	-	2153486..2153587 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU512_RS11080 (KU512_11070)	-	2153709..2154164 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU512_RS11085 (KU512_11075)	-	2154409..2155170 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=585553 KU512_RS11055 WP_000143419.1 2150015..2150902(-) (braS) [Staphylococcus aureus strain 359]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=585553 KU512_RS11055 WP_000143419.1 2150015..2150902(-) (braS) [Staphylococcus aureus strain 359]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997