Detailed information NTG0585512

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KU515_RS07075
• Genome accession: NZ_CP077932
• Coordinates: 1408374..1409417 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 194
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1403374..1414417

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU515_RS07045 (KU515_07025)	-	1403795..1405042 (-)	1248	WP_000656302.1	aminopeptidase	-
KU515_RS07050 (KU515_07030)	-	1405054..1405254 (-)	201	WP_000180459.1	DUF1128 family protein	-
KU515_RS07055 (KU515_07035)	-	1405401..1405865 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
KU515_RS07060 (KU515_07040)	-	1405872..1406147 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KU515_RS07065 (KU515_07045)	-	1406425..1407642 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
KU515_RS07070 (KU515_07050)	vraR	1407755..1408384 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KU515_RS07075 (KU515_07055)	vraS	1408374..1409417 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KU515_RS07080 (KU515_07060)	liaF	1409414..1410115 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KU515_RS07085 (KU515_07065)	-	1410130..1410516 (-)	387	WP_001110184.1	hypothetical protein	-
KU515_RS07090 (KU515_07070)	map	1410733..1411491 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
KU515_RS07095 (KU515_07075)	-	1412079..1413065 (+)	987	WP_000999713.1	FUSC family protein	-
KU515_RS07100 (KU515_07080)	-	1413243..1413656 (-)	414	WP_001622129.1	hypothetical protein	-
KU515_RS07105 (KU515_07085)	-	1413685..1413794 (-)	110	Protein_1376	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=585512 KU515_RS07075 WP_001017131.1 1408374..1409417(-) (vraS) [Staphylococcus aureus strain 194]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=585512 KU515_RS07075 WP_001017131.1 1408374..1409417(-) (vraS) [Staphylococcus aureus strain 194]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1