Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KU526_RS12220 Genome accession   NZ_CP077931
Coordinates   2512879..2513595 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 195     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2507879..2518595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU526_RS12200 (KU526_12160) - 2508971..2509921 (+) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -
  KU526_RS12205 (KU526_12165) - 2510070..2511554 (+) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  KU526_RS12210 (KU526_12170) - 2511551..2512510 (+) 960 WP_001253295.1 carbohydrate kinase family protein -
  KU526_RS12215 (KU526_12175) - 2512700..2512807 (-) 108 WP_031785433.1 hypothetical protein -
  KU526_RS12220 (KU526_12180) agrA 2512879..2513595 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  KU526_RS12225 (KU526_12185) agrC 2513614..2514906 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  KU526_RS12230 (KU526_12190) agrD 2514931..2515071 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  KU526_RS12235 (KU526_12195) agrB 2515068..2515637 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  KU526_RS13800 hld 2515927..2516007 (+) 81 WP_000046022.1 delta-hemolysin -
  KU526_RS12245 (KU526_12205) - 2516608..2517393 (-) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  KU526_RS12250 (KU526_12210) - 2517754..2518380 (-) 627 WP_000522375.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=585477 KU526_RS12220 WP_000688492.1 2512879..2513595(-) (agrA) [Staphylococcus aureus strain 195]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=585477 KU526_RS12220 WP_000688492.1 2512879..2513595(-) (agrA) [Staphylococcus aureus strain 195]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1