Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KU536_RS03260 Genome accession   NZ_CP077924
Coordinates   638444..639160 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 200     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 633444..644160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU536_RS03245 (KU536_03215) - 634531..635481 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  KU536_RS03250 (KU536_03220) - 635630..637114 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  KU536_RS03255 (KU536_03225) - 637111..638070 (+) 960 WP_001253294.1 carbohydrate kinase family protein -
  KU536_RS03260 (KU536_03230) agrA 638444..639160 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  KU536_RS03265 (KU536_03235) agrC 639179..640471 (-) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  KU536_RS03270 (KU536_03240) agrD 640496..640636 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  KU536_RS03275 (KU536_03245) agrB 640633..641202 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  KU536_RS13360 hld 641492..641572 (+) 81 WP_000046022.1 delta-hemolysin -
  KU536_RS03285 (KU536_03255) - 642174..642959 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  KU536_RS03290 (KU536_03260) - 643267..643893 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=585277 KU536_RS03260 WP_000688492.1 638444..639160(-) (agrA) [Staphylococcus aureus strain 200]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=585277 KU536_RS03260 WP_000688492.1 638444..639160(-) (agrA) [Staphylococcus aureus strain 200]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1