Detailed information
Bioinformatically predicted
Overview
| Name | braS | Type | Regulator |
| Locus tag | KU536_RS00040 | Genome accession | NZ_CP077924 |
| Coordinates | 7018..7905 (+) | Length | 295 a.a. |
| NCBI ID | WP_000143420.1 | Uniprot ID | A0A2S6DP21 |
| Organism | Staphylococcus aureus strain 200 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 7156..67491 | 7018..7905 | flank | -749 |
Gene organization within MGE regions
Location: 7018..67491
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KU536_RS00040 (KU536_00040) | braS | 7018..7905 (+) | 888 | WP_000143420.1 | nisin susceptibility-associated two-component system sensor histidine kinase NsaS | Regulator |
| KU536_RS00045 (KU536_00045) | - | 8013..8768 (+) | 756 | WP_000923768.1 | ABC transporter ATP-binding protein | - |
| KU536_RS00050 (KU536_00050) | - | 8765..10765 (+) | 2001 | WP_000776741.1 | ABC transporter permease | - |
| KU536_RS00055 (KU536_00055) | - | 11434..11547 (+) | 114 | WP_014937089.1 | hypothetical protein | - |
| KU536_RS00060 (KU536_00060) | - | 11929..12189 (+) | 261 | WP_014937088.1 | hypothetical protein | - |
| KU536_RS00065 (KU536_00065) | - | 12199..12696 (+) | 498 | WP_001065267.1 | glutathione peroxidase | - |
| KU536_RS00070 (KU536_00070) | - | 12804..12896 (-) | 93 | WP_031774855.1 | hypothetical protein | - |
| KU536_RS00075 (KU536_00075) | - | 13087..14967 (+) | 1881 | WP_000775147.1 | assimilatory sulfite reductase (NADPH) flavoprotein subunit | - |
| KU536_RS00080 (KU536_00080) | - | 15033..15641 (+) | 609 | WP_001057046.1 | NAD(P)-binding protein | - |
| KU536_RS00085 (KU536_00085) | - | 15714..15827 (+) | 114 | WP_001807931.1 | hypothetical protein | - |
| KU536_RS00090 (KU536_00090) | - | 16130..17500 (+) | 1371 | WP_001083496.1 | CitMHS family transporter | - |
| KU536_RS00095 (KU536_00095) | nrdD | 17747..19597 (+) | 1851 | WP_001071718.1 | anaerobic ribonucleoside-triphosphate reductase | - |
| KU536_RS00100 (KU536_00100) | nrdG | 19594..20130 (+) | 537 | WP_000173332.1 | anaerobic ribonucleoside-triphosphate reductase activating protein | - |
| KU536_RS00105 (KU536_00105) | - | 20229..20339 (+) | 111 | WP_001826007.1 | hypothetical protein | - |
| KU536_RS00110 (KU536_00110) | - | 20355..20516 (-) | 162 | WP_001807465.1 | hypothetical protein | - |
| KU536_RS00115 (KU536_00115) | - | 20648..22270 (+) | 1623 | WP_000711870.1 | BCCT family transporter | - |
| KU536_RS00120 (KU536_00120) | cudC | 22439..23002 (-) | 564 | WP_000198596.1 | choline uptake/conversion transcriptional regulator CudC | - |
| KU536_RS00125 (KU536_00125) | - | 23091..23186 (-) | 96 | WP_001789908.1 | hypothetical protein | - |
| KU536_RS00130 (KU536_00130) | betB | 23255..24745 (+) | 1491 | WP_000421708.1 | betaine-aldehyde dehydrogenase | - |
| KU536_RS00135 (KU536_00135) | betA | 25006..26715 (+) | 1710 | WP_000066527.1 | choline dehydrogenase | - |
| KU536_RS00140 (KU536_00140) | - | 26993..27205 (+) | 213 | WP_000011688.1 | sterile alpha motif-like domain-containing protein | - |
| KU536_RS00145 (KU536_00145) | - | 27485..27927 (+) | 443 | Protein_28 | antibiotic biosynthesis monooxygenase family protein | - |
| KU536_RS00150 (KU536_00150) | mbcS | 28121..29719 (+) | 1599 | WP_001172340.1 | acyl-CoA synthetase MbcS | - |
| KU536_RS00155 (KU536_00155) | - | 29779..30110 (-) | 332 | Protein_30 | hypothetical protein | - |
| KU536_RS00160 (KU536_00160) | lqo | 30406..31902 (+) | 1497 | WP_001130051.1 | L-lactate dehydrogenase (quinone) | - |
| KU536_RS00165 (KU536_00165) | - | 32097..32987 (-) | 891 | WP_001031407.1 | fructose bisphosphate aldolase | - |
| KU536_RS00170 (KU536_00170) | - | 33110..33526 (-) | 417 | WP_001237624.1 | hypothetical protein | - |
| KU536_RS00175 (KU536_00175) | - | 33780..35117 (+) | 1338 | WP_000030076.1 | aspartate aminotransferase family protein | - |
| KU536_RS00180 (KU536_00180) | - | 35192..35476 (+) | 285 | WP_000134547.1 | hypothetical protein | - |
| KU536_RS00185 (KU536_00185) | - | 35627..35947 (+) | 321 | WP_000805733.1 | DUF961 family protein | - |
| KU536_RS00190 (KU536_00190) | - | 35961..36263 (+) | 303 | WP_000386891.1 | hypothetical protein | - |
| KU536_RS00195 (KU536_00195) | - | 36438..37529 (+) | 1092 | WP_000172938.1 | replication initiation factor domain-containing protein | - |
| KU536_RS00200 (KU536_00200) | - | 37590..38645 (+) | 1056 | WP_225805657.1 | conjugal transfer protein | - |
| KU536_RS00205 (KU536_00205) | - | 38650..38910 (+) | 261 | WP_000015642.1 | TcpD family membrane protein | - |
| KU536_RS00210 (KU536_00210) | - | 38922..39305 (+) | 384 | WP_000358146.1 | TcpE family conjugal transfer membrane protein | - |
| KU536_RS00215 (KU536_00215) | - | 39340..41835 (+) | 2496 | WP_001049264.1 | ATP-binding protein | - |
| KU536_RS00220 (KU536_00220) | - | 41889..43247 (+) | 1359 | WP_001251198.1 | FtsK/SpoIIIE domain-containing protein | - |
| KU536_RS00225 (KU536_00225) | - | 43252..45099 (+) | 1848 | WP_225805656.1 | CD3337/EF1877 family mobilome membrane protein | - |
| KU536_RS00230 (KU536_00230) | - | 45089..46135 (+) | 1047 | WP_000247474.1 | CHAP domain-containing protein | - |
| KU536_RS00235 (KU536_00235) | - | 46142..46732 (+) | 591 | WP_000810444.1 | hypothetical protein | - |
| KU536_RS00240 (KU536_00240) | - | 46788..47144 (+) | 357 | WP_001255379.1 | cystatin-like fold lipoprotein | - |
| KU536_RS00245 (KU536_00245) | - | 47253..47756 (+) | 504 | WP_000746374.1 | transposase | - |
| KU536_RS00250 (KU536_00250) | - | 47785..48273 (+) | 489 | WP_164022204.1 | IS30 family transposase | - |
| KU536_RS00255 (KU536_00255) | - | 48554..50002 (-) | 1449 | WP_000534420.1 | APC family permease | - |
| KU536_RS00260 (KU536_00260) | - | 50689..51648 (+) | 960 | WP_000846637.1 | L-lactate dehydrogenase | - |
| KU536_RS00265 (KU536_00265) | budA | 51925..52629 (+) | 705 | WP_000186114.1 | acetolactate decarboxylase | - |
| KU536_RS00270 (KU536_00270) | - | 52715..53575 (-) | 861 | WP_000953575.1 | oxidoreductase | - |
| KU536_RS00275 (KU536_00275) | panB | 53648..54466 (+) | 819 | WP_000860047.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| KU536_RS00280 (KU536_00280) | panC | 54459..55310 (+) | 852 | WP_000163736.1 | pantoate--beta-alanine ligase | - |
| KU536_RS00285 (KU536_00285) | panD | 55312..55695 (+) | 384 | WP_000621530.1 | aspartate 1-decarboxylase | - |
| KU536_RS00290 (KU536_00290) | - | 55824..57506 (-) | 1683 | WP_001071573.1 | CocE/NonD family hydrolase | - |
| KU536_RS00295 (KU536_00295) | - | 57563..57671 (+) | 109 | Protein_58 | hypothetical protein | - |
| KU536_RS00300 (KU536_00300) | - | 57649..58236 (+) | 588 | WP_000151119.1 | TetR/AcrR family transcriptional regulator | - |
| KU536_RS00305 (KU536_00305) | - | 58317..58766 (-) | 450 | WP_000125707.1 | VOC family protein | - |
| KU536_RS00310 (KU536_00310) | - | 59120..59842 (+) | 723 | WP_000606210.1 | epoxyqueuosine reductase QueH | - |
| KU536_RS00315 (KU536_00315) | - | 60028..60303 (-) | 276 | WP_001051114.1 | hypothetical protein | - |
| KU536_RS00320 (KU536_00320) | - | 60458..61522 (-) | 1065 | WP_000277417.1 | quinone-dependent dihydroorotate dehydrogenase | - |
| KU536_RS00325 (KU536_00325) | - | 61740..62606 (+) | 867 | WP_001005518.1 | fructosamine kinase family protein | - |
| KU536_RS00330 (KU536_00330) | - | 62947..63225 (+) | 279 | WP_001825991.1 | TIGR04197 family type VII secretion effector | - |
| KU536_RS00335 (KU536_00335) | - | 63240..63608 (+) | 369 | WP_000066365.1 | hypothetical protein | - |
| KU536_RS00340 (KU536_00340) | - | 63596..63892 (+) | 297 | WP_000447707.1 | DUF4176 domain-containing protein | - |
| KU536_RS00345 (KU536_00345) | - | 64228..65334 (+) | 1107 | WP_001163753.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| KU536_RS00350 (KU536_00350) | - | 65328..66668 (+) | 1341 | WP_000895202.1 | nucleoside recognition domain-containing protein | - |
Sequence
Protein
Download Length: 295 a.a. Molecular weight: 34045.32 Da Isoelectric Point: 5.8962
>NTDB_id=585273 KU536_RS00040 WP_000143420.1 7018..7905(+) (braS) [Staphylococcus aureus strain 200]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE
Nucleotide
Download Length: 888 bp
>NTDB_id=585273 KU536_RS00040 WP_000143420.1 7018..7905(+) (braS) [Staphylococcus aureus strain 200]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| braS | Staphylococcus aureus N315 |
99.322 |
100 |
0.993 |