Detailed information NTG0585222

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU538_RS10380
• Genome accession: NZ_CP077922
• Coordinates: 2064063..2064950 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 202
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2059063..2069950

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU538_RS10350 (KU538_10280)	-	2059072..2059164 (+)	93	WP_031774855.1	hypothetical protein	-
KU538_RS10355 (KU538_10285)	-	2059272..2059769 (-)	498	WP_001065267.1	glutathione peroxidase	-
KU538_RS10360 (KU538_10290)	-	2059779..2060039 (-)	261	WP_014937088.1	hypothetical protein	-
KU538_RS10365 (KU538_10295)	-	2060421..2060534 (-)	114	WP_014937089.1	hypothetical protein	-
KU538_RS10370 (KU538_10300)	-	2061203..2063203 (-)	2001	WP_000776741.1	ABC transporter permease	-
KU538_RS10375 (KU538_10305)	-	2063200..2063955 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
KU538_RS10380 (KU538_10310)	braS	2064063..2064950 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU538_RS10385 (KU538_10315)	braR	2064961..2065626 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU538_RS10390 (KU538_10320)	-	2065652..2065852 (-)	201	WP_000604731.1	hypothetical protein	-
KU538_RS10395 (KU538_10325)	-	2066050..2067474 (+)	1425	WP_000953736.1	alkaline phosphatase	-
KU538_RS13465	-	2067534..2067635 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU538_RS10405 (KU538_10335)	-	2067757..2068212 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU538_RS10410 (KU538_10340)	-	2068456..2069217 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=585222 KU538_RS10380 WP_000143420.1 2064063..2064950(-) (braS) [Staphylococcus aureus strain 202]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=585222 KU538_RS10380 WP_000143420.1 2064063..2064950(-) (braS) [Staphylococcus aureus strain 202]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993