Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KU525_RS09550 Genome accession   NZ_CP077920
Coordinates   1939561..1940277 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 277     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1934561..1945277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU525_RS09530 (KU525_09575) - 1935653..1936603 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  KU525_RS09535 (KU525_09580) - 1936752..1938236 (+) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  KU525_RS09540 (KU525_09585) - 1938233..1939192 (+) 960 WP_001253310.1 carbohydrate kinase family protein -
  KU525_RS09545 (KU525_09590) - 1939380..1939489 (-) 110 Protein_1871 hypothetical protein -
  KU525_RS09550 (KU525_09595) agrA 1939561..1940277 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  KU525_RS09555 (KU525_09600) agrC 1940296..1941588 (-) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  KU525_RS09560 (KU525_09605) agrD 1941613..1941753 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  KU525_RS09565 (KU525_09610) agrB 1941750..1942319 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  KU525_RS13540 hld 1942609..1942689 (+) 81 WP_000046022.1 delta-hemolysin -
  KU525_RS09575 (KU525_09620) - 1943286..1944071 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  KU525_RS09580 (KU525_09625) - 1944432..1945058 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=585121 KU525_RS09550 WP_000688498.1 1939561..1940277(-) (agrA) [Staphylococcus aureus strain 277]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=585121 KU525_RS09550 WP_000688498.1 1939561..1940277(-) (agrA) [Staphylococcus aureus strain 277]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996