Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   KU525_RS06140 Genome accession   NZ_CP077920
Coordinates   1279365..1280030 (+) Length   221 a.a.
NCBI ID   WP_000697887.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 277     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1274365..1285030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU525_RS06115 (KU525_06095) - 1275773..1276534 (+) 762 WP_000323448.1 alpha/beta hydrolase -
  KU525_RS06120 (KU525_06100) - 1276779..1277234 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  KU525_RS13535 - 1277356..1277457 (+) 102 WP_000731972.1 SE2200 family small protein -
  KU525_RS06130 (KU525_06110) - 1277517..1278941 (-) 1425 WP_000953744.1 alkaline phosphatase -
  KU525_RS06135 (KU525_06115) - 1279139..1279339 (+) 201 WP_000604727.1 hypothetical protein -
  KU525_RS06140 (KU525_06120) braR 1279365..1280030 (+) 666 WP_000697887.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  KU525_RS06145 (KU525_06125) braS 1280041..1280928 (+) 888 WP_000143419.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  KU525_RS06150 (KU525_06130) - 1281036..1281791 (+) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  KU525_RS06155 (KU525_06135) - 1281788..1283788 (+) 2001 WP_000776733.1 ABC transporter permease -
  KU525_RS06160 (KU525_06140) - 1284447..1284560 (+) 114 WP_011447078.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25369.39 Da        Isoelectric Point: 4.5872

>NTDB_id=585115 KU525_RS06140 WP_000697887.1 1279365..1280030(+) (braR) [Staphylococcus aureus strain 277]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQNQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQSIQLSLTELQILN
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=585115 KU525_RS06140 WP_000697887.1 1279365..1280030(+) (braR) [Staphylococcus aureus strain 277]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAGAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAAAATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCAATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAT
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

98.19

100

0.982