Detailed information NTG0585041

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU509_RS05790
• Genome accession: NZ_CP077917
• Coordinates: 1111992..1112879 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 280
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1106992..1117879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU509_RS05760 (KU509_05815)	-	1107020..1107103 (+)	84	WP_031797553.1	hypothetical protein	-
KU509_RS05765 (KU509_05820)	-	1107211..1107708 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU509_RS05770 (KU509_05825)	-	1107718..1107978 (-)	261	WP_001789307.1	hypothetical protein	-
KU509_RS05775 (KU509_05830)	-	1108360..1108473 (-)	114	WP_011447078.1	hypothetical protein	-
KU509_RS05780 (KU509_05835)	-	1109132..1111132 (-)	2001	WP_000776733.1	ABC transporter permease	-
KU509_RS05785 (KU509_05840)	-	1111129..1111884 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU509_RS05790 (KU509_05845)	braS	1111992..1112879 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU509_RS05795 (KU509_05850)	braR	1112890..1113555 (-)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU509_RS05800 (KU509_05855)	-	1113581..1113781 (-)	201	WP_000604727.1	hypothetical protein	-
KU509_RS05805 (KU509_05860)	-	1113979..1115403 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KU509_RS13580	-	1115463..1115564 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU509_RS05815 (KU509_05870)	-	1115686..1116141 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU509_RS05820 (KU509_05875)	-	1116386..1117147 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=585041 KU509_RS05790 WP_000143419.1 1111992..1112879(-) (braS) [Staphylococcus aureus strain 280]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=585041 KU509_RS05790 WP_000143419.1 1111992..1112879(-) (braS) [Staphylococcus aureus strain 280]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997