Detailed information NTG0584987

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU502_RS05010
• Genome accession: NZ_CP077916
• Coordinates: 966091..966978 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 281
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 961091..971978

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU502_RS04980 (KU502_05035)	-	961119..961202 (+)	84	WP_031797553.1	hypothetical protein	-
KU502_RS04985 (KU502_05040)	-	961310..961807 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU502_RS04990 (KU502_05045)	-	961817..962077 (-)	261	WP_001789307.1	hypothetical protein	-
KU502_RS04995 (KU502_05050)	-	962459..962572 (-)	114	WP_011447078.1	hypothetical protein	-
KU502_RS05000 (KU502_05055)	-	963231..965231 (-)	2001	WP_000776733.1	ABC transporter permease	-
KU502_RS05005 (KU502_05060)	-	965228..965983 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU502_RS05010 (KU502_05065)	braS	966091..966978 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU502_RS05015 (KU502_05070)	braR	966989..967654 (-)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU502_RS05020 (KU502_05075)	-	967680..967880 (-)	201	WP_000604727.1	hypothetical protein	-
KU502_RS05025 (KU502_05080)	-	968078..969502 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KU502_RS13550	-	969562..969663 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU502_RS05035 (KU502_05090)	-	969785..970240 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU502_RS05040 (KU502_05095)	-	970485..971246 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=584987 KU502_RS05010 WP_000143419.1 966091..966978(-) (braS) [Staphylococcus aureus strain 281]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584987 KU502_RS05010 WP_000143419.1 966091..966978(-) (braS) [Staphylococcus aureus strain 281]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997