Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU527_RS11955 Genome accession   NZ_CP077908
Coordinates   2426228..2426797 (+) Length   189 a.a.
NCBI ID   WP_000872878.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 322     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2421228..2431797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU527_RS11930 (KU527_11900) cysE 2422441..2423088 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  KU527_RS11935 (KU527_11905) cysS 2423072..2424472 (+) 1401 WP_000631980.1 cysteine--tRNA ligase -
  KU527_RS11940 (KU527_11910) - 2424465..2424869 (+) 405 WP_000370179.1 Mini-ribonuclease 3 -
  KU527_RS11945 (KU527_11915) rlmB 2424877..2425623 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU527_RS11950 (KU527_11920) - 2425623..2426147 (+) 525 WP_000664731.1 NYN domain-containing protein -
  KU527_RS11955 (KU527_11925) sigH 2426228..2426797 (+) 570 WP_000872878.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU527_RS11960 (KU527_11930) rpmG 2426912..2427055 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU527_RS11965 (KU527_11935) secE 2427111..2427293 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU527_RS11970 (KU527_11940) nusG 2427306..2427854 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU527_RS11975 (KU527_11945) rplK 2428035..2428457 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU527_RS11980 (KU527_11950) rplA 2428665..2429357 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU527_RS11985 (KU527_11955) rplJ 2429629..2430129 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU527_RS11990 (KU527_11960) rplL 2430172..2430540 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU527_RS11995 (KU527_11965) - 2430715..2431323 (+) 609 WP_000020295.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=584885 KU527_RS11955 WP_000872878.1 2426228..2426797(+) (sigH) [Staphylococcus aureus strain 322]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCVIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=584885 KU527_RS11955 WP_000872878.1 2426228..2426797(+) (sigH) [Staphylococcus aureus strain 322]
TTGAAATATGATTTGACAACTCAAGATAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGTAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979