Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KU527_RS05965 Genome accession   NZ_CP077908
Coordinates   1179425..1180141 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 322     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1174425..1185141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU527_RS05935 (KU527_05915) - 1174640..1175266 (+) 627 WP_000522375.1 nitroreductase family protein -
  KU527_RS05940 (KU527_05920) - 1175627..1176412 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  KU527_RS14180 hld 1177013..1177093 (-) 81 WP_000046022.1 delta-hemolysin -
  KU527_RS05950 (KU527_05930) agrB 1177383..1177952 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  KU527_RS05955 (KU527_05935) agrD 1177949..1178089 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  KU527_RS05960 (KU527_05940) agrC 1178114..1179406 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  KU527_RS05965 (KU527_05945) agrA 1179425..1180141 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  KU527_RS05970 (KU527_05950) - 1180213..1180320 (+) 108 WP_031785433.1 hypothetical protein -
  KU527_RS05975 (KU527_05955) - 1180510..1181469 (-) 960 WP_001253295.1 carbohydrate kinase family protein -
  KU527_RS05980 (KU527_05960) - 1181466..1182950 (-) 1485 WP_061104804.1 sucrose-6-phosphate hydrolase -
  KU527_RS05985 (KU527_05965) - 1183099..1184049 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=584874 KU527_RS05965 WP_000688492.1 1179425..1180141(+) (agrA) [Staphylococcus aureus strain 322]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=584874 KU527_RS05965 WP_000688492.1 1179425..1180141(+) (agrA) [Staphylococcus aureus strain 322]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1