Detailed information NTG0584805

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU505_RS00150
• Genome accession: NZ_CP077899
• Coordinates: 30535..31422 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143414.1
• Uniprot ID: A0A6B0AX73
• Organism: Staphylococcus aureus strain 324
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 25535..36422

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU505_RS00120 (KU505_00120)	-	25542..25630 (+)	89	Protein_23	hypothetical protein	-
KU505_RS00125 (KU505_00125)	-	25738..26235 (-)	498	WP_001065267.1	glutathione peroxidase	-
KU505_RS00130 (KU505_00130)	-	26245..26505 (-)	261	WP_072468805.1	hypothetical protein	-
KU505_RS00135 (KU505_00135)	-	26887..27000 (-)	114	WP_072468803.1	hypothetical protein	-
KU505_RS00140 (KU505_00140)	-	27675..29675 (-)	2001	WP_225805942.1	ABC transporter permease	-
KU505_RS00145 (KU505_00145)	-	29672..30427 (-)	756	WP_000923765.1	ABC transporter ATP-binding protein	-
KU505_RS00150 (KU505_00150)	braS	30535..31422 (-)	888	WP_000143414.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU505_RS00155 (KU505_00155)	braR	31433..32098 (-)	666	WP_000697881.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU505_RS00160 (KU505_00160)	-	32124..32324 (-)	201	WP_000604722.1	hypothetical protein	-
KU505_RS00165 (KU505_00165)	-	32522..33946 (+)	1425	WP_000953745.1	alkaline phosphatase	-
KU505_RS15740	-	34006..34107 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU505_RS00175 (KU505_00175)	-	34229..34684 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU505_RS00180 (KU505_00180)	-	34929..35690 (-)	762	WP_000323454.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34073.33 Da
• Isoelectric Point: 5.6141

>NTDB_id=584805 KU505_RS00150 WP_000143414.1 30535..31422(-) (braS) [Staphylococcus aureus strain 324]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKDDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSTGIGLFIVKQISNHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584805 KU505_RS00150 WP_000143414.1 30535..31422(-) (braS) [Staphylococcus aureus strain 324]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAGATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCGAATGTTGTGAATCGTGTTCGTCAAGAGGTAATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATAAACAATATTATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGAATCGGTATTAGTGAGGCAGACTTACCTAAA
ATATTCGACAAAGGTTATTCGGGGTATAATGGACAACGTCAAAGTAATTCAACTGGGATTGGCTTATTTATTGTAAAGCA
AATTTCAAATCACACTAATCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A6B0AX73

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.305	100	0.983