Detailed information NTG0584795

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KU503_RS09395
• Genome accession: NZ_CP077898
• Coordinates: 1890667..1891710 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 327
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1885667..1896710

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU503_RS09365 (KU503_09325)	-	1886088..1887278 (-)	1191	WP_411896787.1	aminopeptidase	-
KU503_RS09370 (KU503_09330)	-	1887347..1887547 (-)	201	WP_000180459.1	DUF1128 family protein	-
KU503_RS09375 (KU503_09335)	-	1887694..1888158 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
KU503_RS09380 (KU503_09340)	-	1888165..1888440 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KU503_RS09385 (KU503_09345)	-	1888718..1889935 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
KU503_RS09390 (KU503_09350)	vraR	1890048..1890677 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KU503_RS09395 (KU503_09355)	vraS	1890667..1891710 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KU503_RS09400 (KU503_09360)	liaF	1891707..1892408 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KU503_RS09405 (KU503_09365)	-	1892423..1892809 (-)	387	WP_001110184.1	hypothetical protein	-
KU503_RS09410 (KU503_09370)	map	1893026..1893784 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
KU503_RS09415 (KU503_09375)	-	1894315..1895301 (+)	987	WP_000999713.1	FUSC family protein	-
KU503_RS09420 (KU503_09380)	-	1895479..1895892 (-)	414	WP_001622129.1	hypothetical protein	-
KU503_RS09425 (KU503_09385)	-	1895921..1896030 (-)	110	Protein_1823	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=584795 KU503_RS09395 WP_001017131.1 1890667..1891710(-) (vraS) [Staphylococcus aureus strain 327]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=584795 KU503_RS09395 WP_001017131.1 1890667..1891710(-) (vraS) [Staphylococcus aureus strain 327]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1