Detailed information    

insolico Bioinformatically predicted

Overview

Name   recQ   Type   Machinery gene
Locus tag   MYL46_RS23135 Genome accession   NZ_CP095801
Coordinates   4764588..4766417 (-) Length   609 a.a.
NCBI ID   WP_000035580.1    Uniprot ID   B7LU33
Organism   Escherichia coli strain E166     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4759588..4771417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL46_RS23110 (MYL46_23010) bioP 4760306..4761205 (-) 900 WP_001196241.1 biotin transporter -
  MYL46_RS23115 (MYL46_23015) yigL 4761281..4762081 (-) 801 WP_000285360.1 sugar/pyridoxal phosphate phosphatase YigL -
  MYL46_RS23120 (MYL46_23020) pldB 4762089..4763111 (-) 1023 WP_000487654.1 lysophospholipase L2 -
  MYL46_RS23125 (MYL46_23025) rhtB 4763222..4763842 (+) 621 WP_000171701.1 homoserine/homoserine lactone efflux protein -
  MYL46_RS23130 (MYL46_23030) rhtC 4763904..4764524 (-) 621 WP_000928844.1 threonine export protein RhtC -
  MYL46_RS23135 (MYL46_23035) recQ 4764588..4766417 (-) 1830 WP_000035580.1 ATP-dependent DNA helicase RecQ Machinery gene
  MYL46_RS23140 (MYL46_23040) pldA 4766542..4767411 (-) 870 WP_001259697.1 phospholipase A -
  MYL46_RS23145 (MYL46_23045) yigI 4767576..4768043 (+) 468 WP_001277142.1 acyl-CoA thioesterase YigI -
  MYL46_RS23150 (MYL46_23050) rarD 4768095..4768985 (+) 891 WP_000379996.1 EamA family transporter RarD -
  MYL46_RS23155 (MYL46_23055) - 4769296..4770144 (+) 849 WP_001059675.1 YPO3983 family protein -
  MYL46_RS23160 (MYL46_23060) - 4770141..4770638 (+) 498 WP_000837559.1 DUF943 family protein -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 68364.49 Da        Isoelectric Point: 7.0906

>NTDB_id=584744 MYL46_RS23135 WP_000035580.1 4764588..4766417(-) (recQ) [Escherichia coli strain E166]
MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKD
QVDQLQANGVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLMEKFKPLDQLMRYVQEQRGKSGI
IYCNSRAKVEDTAARLQSKGISAAAYHAGLENDVRADVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESY
YQETGRAGRDGLPAEAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGRQEPCGNC
DICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDYGHDKLKVYGMGRDKSHEHWVSVIRQLIHLG
LVTQNIAQHSALQLTEAARPVLRGESSLQLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFND
ATLIEMAEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=584744 MYL46_RS23135 WP_000035580.1 4764588..4766417(-) (recQ) [Escherichia coli strain E166]
GTGGCGCAGGCGGAAGTGTTGAATCTGGAGTCCGGAGCTAAACAGGTTTTACAAGAAACCTTTGGCTACCAACAGTTTCG
CCCCGGCCAGGAAGAGATTATCGACACTGTGCTTTCCGGTCGCGATTGCCTGGTCGTCATGCCCACCGGTGGCGGAAAAT
CCCTTTGCTATCAAATTCCTGCCTTATTGCTAAACGGCCTTACCGTGGTTGTTTCACCGCTGATTTCGTTGATGAAAGAT
CAGGTGGATCAACTGCAAGCCAACGGCGTGGCGGCGGCGTGCCTTAACTCGACGCAAACCCGCGAACAGCAACTTGAAGT
GATGACAGGCTGTCGCACCGGGCAAATTCGTCTGCTTTATATCGCCCCGGAACGCCTGATGCTGGATAACTTTCTTGAGC
ATCTGGCGCACTGGAATCCGGTGTTATTAGCCGTTGATGAAGCGCACTGTATCTCCCAATGGGGCCACGATTTCCGCCCG
GAATATGCCGCGCTCGGTCAGTTGCGCCAGCGGTTCCCGACGCTGCCGTTTATGGCGCTGACCGCCACCGCCGACGACAC
CACGCGGCAGGATATCGTGCGCCTGCTGGGGCTGAACGATCCGCTGATTCAAATTAGCAGTTTTGACCGTCCGAATATTC
GCTACATGTTGATGGAGAAGTTCAAACCGCTCGATCAGCTGATGCGCTACGTGCAGGAACAACGCGGTAAGTCGGGGATT
ATTTACTGTAATAGTCGTGCGAAAGTAGAAGACACCGCCGCGCGTCTGCAAAGCAAGGGTATCAGCGCAGCGGCTTATCA
CGCCGGGCTTGAAAACGATGTCCGTGCGGACGTGCAGGAAAAATTCCAGCGCGATGACCTGCAAATTGTGGTGGCGACGG
TGGCGTTCGGCATGGGCATCAATAAACCAAACGTTCGCTTCGTGGTGCATTTTGATATTCCGCGCAACATTGAATCCTAT
TATCAGGAAACCGGACGCGCCGGGCGTGATGGCCTGCCCGCGGAAGCGATGCTGTTTTACGATCCGGCGGATATGGCGTG
GCTGCGTCGTTGTCTGGAAGAGAAACCGCAGGGGCAGTTACAGGATATCGAACGTCATAAACTCAATGCGATGGGCGCGT
TTGCCGAAGCGCAAACTTGCCGTCGTCTGGTATTGCTGAACTATTTTGGCGAAGGGCGGCAGGAGCCGTGCGGGAACTGC
GATATCTGCCTCGATCCGCCGAAACAATACGATGGTTCAACCGATGCTCAGATTGCCCTTTCCACCATTGGTCGTGTGAA
TCAGCGGTTTGGGATGGGCTATGTGGTGGAAGTGATTCGTGGCGCTAATAACCAGCGTATCCGCGACTATGGTCATGACA
AACTGAAAGTCTATGGCATGGGCCGTGATAAAAGCCATGAACATTGGGTGAGCGTGATCCGCCAGCTGATTCACCTCGGC
CTGGTGACGCAAAATATTGCCCAGCATTCTGCCCTACAACTGACAGAGGCTGCGCGTCCGGTGCTGCGCGGCGAATCCTC
TTTGCAACTTGCCGTGCCGCGTATCGTGGCGCTCAAACCGAAAGCGATGCAGAAATCGTTCGGCGGCAACTATGATCGCA
AACTGTTCGCCAAATTACGCAAACTGCGTAAATCGATTGCCGATGAAAGCAATGTCCCGCCGTACGTGGTATTTAACGAC
GCAACCTTGATTGAGATGGCGGAACAGATGCCGATCACTGCCAGCGAAATGCTCAGCGTTAACGGCGTTGGGATGCGCAA
GCTGGAACGCTTTGGCAAACCGTTTATGGCGCTGATTCGTGCGCATGTCGATGGCGATGACGAAGAGTAG

Domains

Predicted by InterProScan.

RecQ zinc-binding (RecQ_Zn_bind)

(343-404)

Helicase conserved C-terminal domain (Helicase_C)

(223-330)

DEAD/DEAH box helicase (DEAD)

(28-187)

HRDC domain (HRDC)

(533-599)

RQC domain (RQC)

(406-514)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LU33

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recQ Bacillus subtilis subsp. subtilis str. 168

40.372

97.209

0.392