Detailed information NTG0584682

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU540_RS02755
• Genome accession: NZ_CP077894
• Coordinates: 596834..597721 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143414.1
• Uniprot ID: A0A6B0AX73
• Organism: Staphylococcus aureus strain 329
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 591834..602721

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU540_RS02725 (KU540_02700)	-	592566..593327 (+)	762	WP_000323454.1	alpha/beta hydrolase	-
KU540_RS02730 (KU540_02705)	-	593572..594027 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU540_RS14265	-	594149..594250 (+)	102	WP_000731972.1	SE2200 family small protein	-
KU540_RS02740 (KU540_02715)	-	594310..595734 (-)	1425	WP_000953745.1	alkaline phosphatase	-
KU540_RS02745 (KU540_02720)	-	595932..596132 (+)	201	WP_000604722.1	hypothetical protein	-
KU540_RS02750 (KU540_02725)	braR	596158..596823 (+)	666	WP_000697881.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU540_RS02755 (KU540_02730)	braS	596834..597721 (+)	888	WP_000143414.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU540_RS02760 (KU540_02735)	-	597829..598584 (+)	756	WP_000923765.1	ABC transporter ATP-binding protein	-
KU540_RS02765 (KU540_02740)	-	598581..600581 (+)	2001	WP_225805942.1	ABC transporter permease	-
KU540_RS02770 (KU540_02745)	-	601256..601369 (+)	114	WP_072468803.1	hypothetical protein	-
KU540_RS02775 (KU540_02750)	-	601751..602011 (+)	261	WP_072468805.1	hypothetical protein	-
KU540_RS02780 (KU540_02755)	-	602021..602518 (+)	498	WP_001065267.1	glutathione peroxidase	-
KU540_RS02785 (KU540_02760)	-	602626..602714 (-)	89	Protein_541	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34073.33 Da
• Isoelectric Point: 5.6141

>NTDB_id=584682 KU540_RS02755 WP_000143414.1 596834..597721(+) (braS) [Staphylococcus aureus strain 329]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKDDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSTGIGLFIVKQISNHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584682 KU540_RS02755 WP_000143414.1 596834..597721(+) (braS) [Staphylococcus aureus strain 329]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAGATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCGAATGTTGTGAATCGTGTTCGTCAAGAGGTAATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATAAACAATATTATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGAATCGGTATTAGTGAGGCAGACTTACCTAAA
ATATTCGACAAAGGTTATTCGGGGTATAATGGACAACGTCAAAGTAATTCAACTGGGATTGGCTTATTTATTGTAAAGCA
AATTTCAAATCACACTAATCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A6B0AX73

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.305	100	0.983