Detailed information NTG0584596

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU539_RS01550
• Genome accession: NZ_CP077889
• Coordinates: 311143..312030 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 333
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 306143..317030

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU539_RS01520 (KU539_01520)	-	306162..306254 (+)	93	WP_010956583.1	hypothetical protein	-
KU539_RS01525 (KU539_01525)	-	306362..306859 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU539_RS01530 (KU539_01530)	-	306869..307129 (-)	261	WP_001789910.1	hypothetical protein	-
KU539_RS01535 (KU539_01535)	-	307511..307624 (-)	114	WP_011447078.1	hypothetical protein	-
KU539_RS01540 (KU539_01540)	-	308283..310283 (-)	2001	WP_000776751.1	ABC transporter permease	-
KU539_RS01545 (KU539_01545)	-	310280..311035 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU539_RS01550 (KU539_01550)	braS	311143..312030 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU539_RS01555 (KU539_01555)	braR	312041..312706 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU539_RS01560 (KU539_01560)	-	312732..312932 (-)	201	WP_000604728.1	hypothetical protein	-
KU539_RS01565 (KU539_01565)	-	313130..314554 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KU539_RS14145	-	314614..314715 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU539_RS01575 (KU539_01575)	-	314837..315292 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU539_RS01580 (KU539_01580)	-	315537..316298 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=584596 KU539_RS01550 WP_000143419.1 311143..312030(-) (braS) [Staphylococcus aureus strain 333]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584596 KU539_RS01550 WP_000143419.1 311143..312030(-) (braS) [Staphylococcus aureus strain 333]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997