Detailed information NTG0584563

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU519_RS04800
• Genome accession: NZ_CP077888
• Coordinates: 888231..889118 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 334
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 883231..894118

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU519_RS04770 (KU519_04780)	-	883250..883342 (+)	93	WP_010956583.1	hypothetical protein	-
KU519_RS04775 (KU519_04785)	-	883450..883947 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU519_RS04780 (KU519_04790)	-	883957..884217 (-)	261	WP_001789910.1	hypothetical protein	-
KU519_RS04785 (KU519_04795)	-	884599..884712 (-)	114	WP_011447078.1	hypothetical protein	-
KU519_RS04790 (KU519_04800)	-	885371..887371 (-)	2001	WP_000776751.1	ABC transporter permease	-
KU519_RS04795 (KU519_04805)	-	887368..888123 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU519_RS04800 (KU519_04810)	braS	888231..889118 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU519_RS04805 (KU519_04815)	braR	889129..889794 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU519_RS04810 (KU519_04820)	-	889820..890020 (-)	201	WP_000604728.1	hypothetical protein	-
KU519_RS04815 (KU519_04825)	-	890218..891642 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KU519_RS13680	-	891702..891803 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU519_RS04825 (KU519_04835)	-	891925..892380 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU519_RS04830 (KU519_04840)	-	892625..893386 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=584563 KU519_RS04800 WP_000143419.1 888231..889118(-) (braS) [Staphylococcus aureus strain 334]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584563 KU519_RS04800 WP_000143419.1 888231..889118(-) (braS) [Staphylococcus aureus strain 334]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997