Detailed information NTG0584549

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU507_RS12555
• Genome accession: NZ_CP077885
• Coordinates: 2445196..2446083 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 355
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2440196..2451083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU507_RS12525 (KU507_12505)	-	2440215..2440307 (+)	93	WP_010956583.1	hypothetical protein	-
KU507_RS12530 (KU507_12510)	-	2440415..2440912 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU507_RS12535 (KU507_12515)	-	2440922..2441182 (-)	261	WP_001789910.1	hypothetical protein	-
KU507_RS12540 (KU507_12520)	-	2441564..2441677 (-)	114	WP_011447078.1	hypothetical protein	-
KU507_RS12545 (KU507_12525)	-	2442336..2444336 (-)	2001	WP_000776751.1	ABC transporter permease	-
KU507_RS12550 (KU507_12530)	-	2444333..2445088 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU507_RS12555 (KU507_12535)	braS	2445196..2446083 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU507_RS12560 (KU507_12540)	braR	2446094..2446759 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU507_RS12565 (KU507_12545)	-	2446785..2446985 (-)	201	WP_000604728.1	hypothetical protein	-
KU507_RS12570 (KU507_12550)	-	2447183..2448607 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KU507_RS14740	-	2448667..2448768 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU507_RS12580 (KU507_12560)	-	2448890..2449345 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU507_RS12585 (KU507_12565)	-	2449590..2450351 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=584549 KU507_RS12555 WP_000143419.1 2445196..2446083(-) (braS) [Staphylococcus aureus strain 355]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584549 KU507_RS12555 WP_000143419.1 2445196..2446083(-) (braS) [Staphylococcus aureus strain 355]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997