Detailed information NTG0584381

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU523_RS13875
• Genome accession: NZ_CP077870
• Coordinates: 2751660..2752547 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 360
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2746660..2757547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU523_RS13845 (KU523_13825)	-	2746679..2746771 (+)	93	WP_010956583.1	hypothetical protein	-
KU523_RS13850 (KU523_13830)	-	2746879..2747376 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU523_RS13855 (KU523_13835)	-	2747386..2747646 (-)	261	WP_001789910.1	hypothetical protein	-
KU523_RS13860 (KU523_13840)	-	2748028..2748141 (-)	114	WP_011447078.1	hypothetical protein	-
KU523_RS13865 (KU523_13845)	-	2748800..2750800 (-)	2001	WP_000776751.1	ABC transporter permease	-
KU523_RS13870 (KU523_13850)	-	2750797..2751552 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU523_RS13875 (KU523_13855)	braS	2751660..2752547 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU523_RS13880 (KU523_13860)	braR	2752558..2753223 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU523_RS13885 (KU523_13865)	-	2753249..2753449 (-)	201	WP_000604728.1	hypothetical protein	-
KU523_RS13890 (KU523_13870)	-	2753647..2755071 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KU523_RS14750	-	2755131..2755232 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU523_RS13900 (KU523_13880)	-	2755354..2755809 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU523_RS13905 (KU523_13885)	-	2756054..2756815 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=584381 KU523_RS13875 WP_000143419.1 2751660..2752547(-) (braS) [Staphylococcus aureus strain 360]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584381 KU523_RS13875 WP_000143419.1 2751660..2752547(-) (braS) [Staphylococcus aureus strain 360]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997