Detailed information NTG0584336

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU517_RS12225
• Genome accession: NZ_CP077869
• Coordinates: 2437990..2438877 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143422.1
• Uniprot ID: A0AB73JC73
• Organism: Staphylococcus aureus strain 365
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2432990..2443877

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU517_RS12195 (KU517_12145)	-	2432999..2433091 (+)	93	WP_010956583.1	hypothetical protein	-
KU517_RS12200 (KU517_12150)	-	2433199..2433696 (-)	498	WP_001065268.1	glutathione peroxidase	-
KU517_RS12205 (KU517_12155)	-	2433706..2433966 (-)	261	WP_011382405.1	hypothetical protein	-
KU517_RS12210 (KU517_12160)	-	2434348..2434461 (-)	114	WP_078065157.1	hypothetical protein	-
KU517_RS12215 (KU517_12165)	-	2435130..2437130 (-)	2001	WP_000776725.1	ABC transporter permease	-
KU517_RS12220 (KU517_12170)	-	2437127..2437882 (-)	756	WP_000923775.1	ABC transporter ATP-binding protein	-
KU517_RS12225 (KU517_12175)	braS	2437990..2438877 (-)	888	WP_000143422.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU517_RS12230 (KU517_12180)	braR	2438888..2439553 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU517_RS12235 (KU517_12185)	-	2439579..2439779 (-)	201	WP_000604725.1	hypothetical protein	-
KU517_RS12240 (KU517_12190)	-	2439977..2441401 (+)	1425	WP_000953738.1	alkaline phosphatase	-
KU517_RS13615	-	2441461..2441562 (-)	102	WP_000731972.1	SE2200 family small protein	-
KU517_RS12250 (KU517_12200)	-	2441684..2442139 (-)	456	WP_000106183.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU517_RS12255 (KU517_12205)	-	2442384..2443145 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34031.29 Da
• Isoelectric Point: 5.8962

>NTDB_id=584336 KU517_RS12225 WP_000143422.1 2437990..2438877(-) (braS) [Staphylococcus aureus strain 365]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGVGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=584336 KU517_RS12225 WP_000143422.1 2437990..2438877(-) (braS) [Staphylococcus aureus strain 365]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTGTTGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99