Detailed information NTG0583795

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KU508_RS00075
• Genome accession: NZ_CP077854
• Coordinates: 10651..11694 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain N4
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 5651..16694

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU508_RS00045 (KU508_00045)	-	6072..7328 (-)	1257	WP_001795108.1	aminopeptidase	-
KU508_RS00050 (KU508_00050)	-	7331..7531 (-)	201	WP_000180460.1	DUF1128 family protein	-
KU508_RS00055 (KU508_00055)	-	7678..8142 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KU508_RS00060 (KU508_00060)	-	8149..8424 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KU508_RS00065 (KU508_00065)	-	8702..9919 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
KU508_RS00070 (KU508_00070)	vraR	10032..10661 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KU508_RS00075 (KU508_00075)	vraS	10651..11694 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KU508_RS00080 (KU508_00080)	liaF	11691..12392 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KU508_RS00085 (KU508_00085)	-	12407..12793 (-)	387	WP_001110179.1	hypothetical protein	-
KU508_RS00090 (KU508_00090)	map	13010..13768 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KU508_RS00095 (KU508_00095)	-	14299..15285 (+)	987	WP_000999717.1	FUSC family protein	-
KU508_RS00100 (KU508_00100)	-	15716..16129 (-)	414	WP_001557448.1	hypothetical protein	-
KU508_RS00105 (KU508_00105)	-	16158..16268 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=583795 KU508_RS00075 WP_001017131.1 10651..11694(-) (vraS) [Staphylococcus aureus strain N4]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=583795 KU508_RS00075 WP_001017131.1 10651..11694(-) (vraS) [Staphylococcus aureus strain N4]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACGCTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1