Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   MU524_RS25040 Genome accession   NZ_CP095271
Coordinates   5114720..5115712 (-) Length   330 a.a.
NCBI ID   WP_000224467.1    Uniprot ID   B7MGH3
Organism   Escherichia coli strain EC9682     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5109720..5120712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU524_RS25030 (MU524_25040) yieP 5112612..5113304 (+) 693 WP_001131161.1 FadR/GntR family transcriptional regulator -
  MU524_RS25035 (MU524_25045) mdtD 5113327..5114754 (+) 1428 WP_001280824.1 multidrug transporter subunit MdtD -
  MU524_RS25040 (MU524_25050) cytR 5114720..5115712 (-) 993 WP_000224467.1 ribose operon transcriptional repressor RbsR Regulator
  MU524_RS25045 (MU524_25055) rbsK 5115716..5116645 (-) 930 WP_001361088.1 ribokinase -
  MU524_RS25050 (MU524_25060) rbsB 5116771..5117661 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  MU524_RS25055 (MU524_25065) rbsC 5117686..5118651 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  MU524_RS25060 (MU524_25070) rbsA 5118656..5120161 (-) 1506 WP_000387779.1 ribose ABC transporter ATP-binding protein RbsA -
  MU524_RS25065 (MU524_25075) rbsD 5120169..5120588 (-) 420 WP_001350412.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36581.88 Da        Isoelectric Point: 5.2141

>NTDB_id=582886 MU524_RS25040 WP_000224467.1 5114720..5115712(-) (cytR) [Escherichia coli strain EC9682]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPALQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=582886 MU524_RS25040 WP_000224467.1 5114720..5115712(-) (cytR) [Escherichia coli strain EC9682]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACAGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTTGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGTAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAGCCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACCGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATTGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCTGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACAACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGGCCCTACAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGTGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(3-48)

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7MGH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364