Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KTR68_RS13210 Genome accession   NZ_CP077757
Coordinates   2692295..2693011 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain WHC07     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2687295..2698011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KTR68_RS13190 - 2688379..2689329 (+) 951 WP_031588340.1 LacI family DNA-binding transcriptional regulator -
  KTR68_RS13195 - 2689478..2690962 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  KTR68_RS13200 - 2690959..2691918 (+) 960 WP_001253314.1 carbohydrate kinase -
  KTR68_RS13205 - 2692106..2692215 (-) 110 Protein_2575 hypothetical protein -
  KTR68_RS13210 agrA 2692295..2693011 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  KTR68_RS13215 agrC 2693030..2694313 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  KTR68_RS13220 agrD 2694343..2694486 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  KTR68_RS13225 - 2694489..2695052 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  KTR68_RS14080 hld 2695342..2695422 (+) 81 WP_000046022.1 delta-hemolysin -
  KTR68_RS13235 - 2696019..2696804 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  KTR68_RS13240 - 2697165..2697791 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=582810 KTR68_RS13210 WP_000688498.1 2692295..2693011(-) (agrA) [Staphylococcus aureus strain WHC07]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=582810 KTR68_RS13210 WP_000688498.1 2692295..2693011(-) (agrA) [Staphylococcus aureus strain WHC07]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996