Detailed information NTG0582769

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KTR65_RS13880
• Genome accession: NZ_CP077755
• Coordinates: 2819134..2820177 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain WHC09
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2814134..2825177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KTR65_RS13850	-	2814679..2814789 (+)	111	WP_031775032.1	hypothetical protein	-
KTR65_RS13855	-	2814818..2815231 (+)	414	WP_001670387.1	hypothetical protein	-
KTR65_RS13860	-	2815662..2816648 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
KTR65_RS13865	map	2817060..2817818 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KTR65_RS13870	-	2818035..2818421 (+)	387	WP_001110179.1	hypothetical protein	-
KTR65_RS13875	liaF	2818436..2819137 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KTR65_RS13880	vraS	2819134..2820177 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KTR65_RS13885	vraR	2820167..2820796 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KTR65_RS13890	-	2820908..2822125 (-)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
KTR65_RS13895	-	2822403..2822678 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
KTR65_RS13900	-	2822685..2823149 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KTR65_RS13905	-	2823296..2823496 (+)	201	WP_000180460.1	DUF1128 family protein	-
KTR65_RS13910	-	2823499..2824755 (+)	1257	WP_001789555.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=582769 KTR65_RS13880 WP_001017131.1 2819134..2820177(+) (vraS) [Staphylococcus aureus strain WHC09]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=582769 KTR65_RS13880 WP_001017131.1 2819134..2820177(+) (vraS) [Staphylococcus aureus strain WHC09]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1