Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KTR65_RS13420 Genome accession   NZ_CP077755
Coordinates   2729710..2730426 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain WHC09     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2724710..2735426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KTR65_RS13400 - 2725794..2726744 (+) 951 WP_031588340.1 LacI family DNA-binding transcriptional regulator -
  KTR65_RS13405 - 2726893..2728377 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  KTR65_RS13410 - 2728374..2729333 (+) 960 WP_001253314.1 carbohydrate kinase -
  KTR65_RS13415 - 2729521..2729630 (-) 110 Protein_2617 hypothetical protein -
  KTR65_RS13420 agrA 2729710..2730426 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  KTR65_RS13425 agrC 2730445..2731728 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  KTR65_RS13430 agrD 2731758..2731901 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  KTR65_RS13435 - 2731904..2732467 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  KTR65_RS14300 hld 2732757..2732837 (+) 81 WP_000046022.1 delta-hemolysin -
  KTR65_RS13445 - 2733434..2734219 (-) 786 WP_217838620.1 carbon-nitrogen family hydrolase -
  KTR65_RS13450 - 2734580..2735206 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=582768 KTR65_RS13420 WP_000688498.1 2729710..2730426(-) (agrA) [Staphylococcus aureus strain WHC09]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=582768 KTR65_RS13420 WP_000688498.1 2729710..2730426(-) (agrA) [Staphylococcus aureus strain WHC09]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996