Detailed information NTG0582635

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KTE72_RS14065
• Genome accession: NZ_CP077741
• Coordinates: 2805772..2806659 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NL1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2800772..2811659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KTE72_RS14035 (KTE72_13930)	-	2800781..2800873 (+)	93	WP_031774855.1	hypothetical protein	-
KTE72_RS14040 (KTE72_13935)	-	2800981..2801478 (-)	498	WP_001065267.1	glutathione peroxidase	-
KTE72_RS14045 (KTE72_13940)	-	2801488..2801748 (-)	261	WP_014937088.1	hypothetical protein	-
KTE72_RS14050 (KTE72_13945)	-	2802130..2802243 (-)	114	WP_014937089.1	hypothetical protein	-
KTE72_RS14055 (KTE72_13950)	-	2802912..2804912 (-)	2001	WP_000776741.1	ABC transporter permease	-
KTE72_RS14060 (KTE72_13955)	-	2804909..2805664 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
KTE72_RS14065 (KTE72_13960)	braS	2805772..2806659 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KTE72_RS14070 (KTE72_13965)	braR	2806670..2807335 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KTE72_RS14075 (KTE72_13970)	-	2807361..2807561 (-)	201	WP_000604731.1	hypothetical protein	-
KTE72_RS14080 (KTE72_13975)	-	2807759..2809183 (+)	1425	WP_000953736.1	alkaline phosphatase	-
KTE72_RS14770	-	2809243..2809344 (-)	102	WP_000731972.1	SE2200 family small protein	-
KTE72_RS14090 (KTE72_13985)	-	2809466..2809921 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KTE72_RS14095 (KTE72_13990)	-	2810165..2810926 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=582635 KTE72_RS14065 WP_000143420.1 2805772..2806659(-) (braS) [Staphylococcus aureus strain NL1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=582635 KTE72_RS14065 WP_000143420.1 2805772..2806659(-) (braS) [Staphylococcus aureus strain NL1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993