Detailed information NTG0582630

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KTE72_RS10450
• Genome accession: NZ_CP077741
• Coordinates: 2093811..2094854 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NL1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2088811..2099854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KTE72_RS10420 (KTE72_10355)	-	2089232..2090488 (-)	1257	WP_074347694.1	aminopeptidase	-
KTE72_RS10425 (KTE72_10360)	-	2090491..2090691 (-)	201	WP_000180460.1	DUF1128 family protein	-
KTE72_RS10430 (KTE72_10365)	-	2090838..2091302 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KTE72_RS10435 (KTE72_10370)	-	2091309..2091584 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KTE72_RS10440 (KTE72_10375)	-	2091862..2093079 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
KTE72_RS10445 (KTE72_10380)	vraR	2093192..2093821 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KTE72_RS10450 (KTE72_10385)	vraS	2093811..2094854 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KTE72_RS10455 (KTE72_10390)	liaF	2094851..2095552 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KTE72_RS10460 (KTE72_10395)	-	2095567..2095953 (-)	387	WP_001110182.1	hypothetical protein	-
KTE72_RS10465 (KTE72_10400)	map	2096170..2096928 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
KTE72_RS10470 (KTE72_10405)	-	2097512..2098498 (+)	987	WP_000999712.1	FUSC family protein	-
KTE72_RS10475 (KTE72_10410)	-	2098687..2099100 (-)	414	WP_025174370.1	hypothetical protein	-
KTE72_RS10480 (KTE72_10415)	-	2099129..2099239 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=582630 KTE72_RS10450 WP_001017131.1 2093811..2094854(-) (vraS) [Staphylococcus aureus strain NL1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=582630 KTE72_RS10450 WP_001017131.1 2093811..2094854(-) (vraS) [Staphylococcus aureus strain NL1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1