Detailed information NTG0582589

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KTE14_RS13750
• Genome accession: NZ_CP077738
• Coordinates: 2765531..2766418 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain UMCG578
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2760531..2771418

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KTE14_RS13720 (KTE14_13615)	-	2760540..2760632 (+)	93	WP_031774855.1	hypothetical protein	-
KTE14_RS13725 (KTE14_13620)	-	2760740..2761237 (-)	498	WP_001065267.1	glutathione peroxidase	-
KTE14_RS13730 (KTE14_13625)	-	2761247..2761507 (-)	261	WP_014937088.1	hypothetical protein	-
KTE14_RS13735 (KTE14_13630)	-	2761889..2762002 (-)	114	WP_014937089.1	hypothetical protein	-
KTE14_RS13740 (KTE14_13635)	-	2762671..2764671 (-)	2001	WP_000776741.1	ABC transporter permease	-
KTE14_RS13745 (KTE14_13640)	-	2764668..2765423 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
KTE14_RS13750 (KTE14_13645)	braS	2765531..2766418 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KTE14_RS13755 (KTE14_13650)	braR	2766429..2767094 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KTE14_RS13760 (KTE14_13655)	-	2767120..2767320 (-)	201	WP_000604731.1	hypothetical protein	-
KTE14_RS13765 (KTE14_13660)	-	2767518..2768942 (+)	1425	WP_000953736.1	alkaline phosphatase	-
KTE14_RS14315	-	2769002..2769103 (-)	102	WP_000731972.1	SE2200 family small protein	-
KTE14_RS13775 (KTE14_13670)	-	2769225..2769680 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KTE14_RS13780 (KTE14_13675)	-	2769924..2770685 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=582589 KTE14_RS13750 WP_000143420.1 2765531..2766418(-) (braS) [Staphylococcus aureus strain UMCG578]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=582589 KTE14_RS13750 WP_000143420.1 2765531..2766418(-) (braS) [Staphylococcus aureus strain UMCG578]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993