Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   VB13_RS05620 Genome accession   NZ_CP077685
Coordinates   1140579..1141616 (-) Length   345 a.a.
NCBI ID   WP_012560824.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M49 591     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1135579..1146616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS05600 (VB13_05775) - 1136329..1136955 (+) 627 WP_002983834.1 A24 family peptidase -
  VB13_RS05605 (VB13_05780) rlmN 1137037..1138116 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  VB13_RS05610 (VB13_05785) - 1138120..1138740 (-) 621 WP_002992791.1 YutD family protein -
  VB13_RS05615 (VB13_05790) - 1139188..1140165 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  VB13_RS05620 (VB13_05795) sepM 1140579..1141616 (-) 1038 WP_012560824.1 SepM family pheromone-processing serine protease Regulator
  VB13_RS05625 (VB13_05800) coaD 1141603..1142094 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  VB13_RS05630 (VB13_05805) rsmD 1142084..1142623 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  VB13_RS05635 (VB13_05810) asnA 1142746..1143738 (-) 993 WP_012560825.1 aspartate--ammonia ligase -
  VB13_RS05640 (VB13_05815) arcC 1144051..1145001 (-) 951 WP_009880962.1 carbamate kinase -
  VB13_RS05645 (VB13_05820) - 1145021..1146352 (-) 1332 WP_009880963.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.20 Da        Isoelectric Point: 9.5788

>NTDB_id=582245 VB13_RS05620 WP_012560824.1 1140579..1141616(-) (sepM) [Streptococcus pyogenes strain M49 591]
MKRLNKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=582245 VB13_RS05620 WP_012560824.1 1140579..1141616(-) (sepM) [Streptococcus pyogenes strain M49 591]
ATGAAAAGACTTAACAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.696

100

0.687