Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | VB13_RS01155 | Genome accession | NZ_CP077685 |
| Coordinates | 208212..209573 (+) | Length | 453 a.a. |
| NCBI ID | WP_002986109.1 | Uniprot ID | A0A4Q1R665 |
| Organism | Streptococcus pyogenes strain M49 591 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 172624..208131 | 208212..209573 | flank | 81 |
Gene organization within MGE regions
Location: 172624..209573
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VB13_RS00995 (VB13_01020) | - | 172624..173820 (+) | 1197 | WP_085634412.1 | glycine betaine/L-proline ABC transporter ATP-binding protein | - |
| VB13_RS01000 (VB13_01025) | - | 173836..175563 (+) | 1728 | WP_012560412.1 | ABC transporter permease/substrate binding protein | - |
| VB13_RS01005 (VB13_01030) | polA | 175694..178336 (+) | 2643 | WP_219050303.1 | DNA polymerase I | - |
| VB13_RS01010 (VB13_01035) | - | 178514..178969 (+) | 456 | WP_009880533.1 | CoA-binding protein | - |
| VB13_RS01015 (VB13_01040) | perR | 179021..179488 (+) | 468 | WP_002986328.1 | peroxide-responsive transcriptional repressor PerR | - |
| VB13_RS01020 | - | 179707..179943 (+) | 237 | WP_014635252.1 | hypothetical protein | - |
| VB13_RS01025 (VB13_01050) | - | 180165..181499 (+) | 1335 | WP_002987923.1 | phosphoadenosine phosphosulfate reductase | - |
| VB13_RS01030 (VB13_01055) | - | 181492..182022 (+) | 531 | WP_002987925.1 | ParB/RepB/Spo0J family partition protein | - |
| VB13_RS01035 | - | 182069..182218 (-) | 150 | Protein_155 | ISL3 family transposase | - |
| VB13_RS01040 | - | 182351..183501 (-) | 1151 | Protein_156 | IS3 family transposase | - |
| VB13_RS01045 (VB13_01080) | - | 183579..184889 (-) | 1311 | WP_002984130.1 | SLC13 family permease | - |
| VB13_RS01050 (VB13_01085) | nadC | 185113..185985 (+) | 873 | WP_002992869.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| VB13_RS01060 (VB13_01100) | - | 187713..188576 (-) | 864 | WP_012560419.1 | DUF975 family protein | - |
| VB13_RS08775 | - | 188613..188798 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| VB13_RS01065 (VB13_01105) | tgt | 188795..189937 (+) | 1143 | WP_011528208.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| VB13_RS01070 (VB13_01110) | - | 190154..190465 (+) | 312 | WP_002987947.1 | CHY zinc finger protein | - |
| VB13_RS01075 (VB13_01115) | - | 190469..191008 (+) | 540 | WP_002986314.1 | biotin transporter BioY | - |
| VB13_RS01080 (VB13_01120) | - | 191148..191927 (+) | 780 | WP_012560420.1 | MBL fold metallo-hydrolase | - |
| VB13_RS01085 (VB13_01125) | tadA | 191927..192442 (+) | 516 | WP_002992549.1 | tRNA adenosine(34) deaminase TadA | - |
| VB13_RS01090 (VB13_01130) | - | 193056..194288 (-) | 1233 | WP_009880892.1 | transglutaminase domain-containing protein | - |
| VB13_RS01100 (VB13_01140) | speG | 194688..195392 (+) | 705 | WP_009880893.1 | streptococcal pyrogenic exotoxin SpeG | - |
| VB13_RS01105 (VB13_01145) | - | 195847..197196 (+) | 1350 | WP_002992560.1 | glucose-6-phosphate isomerase | - |
| VB13_RS01110 (VB13_01155) | - | 197545..199053 (-) | 1509 | WP_023079312.1 | helix-turn-helix domain-containing protein | - |
| VB13_RS01115 (VB13_01165) | - | 199741..200412 (+) | 672 | WP_011184138.1 | rhomboid family intramembrane serine protease | - |
| VB13_RS01120 (VB13_01170) | galU | 200511..201410 (-) | 900 | WP_012560423.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| VB13_RS01125 (VB13_01175) | - | 201443..202459 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| VB13_RS01130 (VB13_01180) | - | 202755..203204 (+) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| VB13_RS01135 (VB13_01185) | - | 203197..204903 (+) | 1707 | WP_009880875.1 | ABC transporter ATP-binding protein | - |
| VB13_RS01140 (VB13_01190) | - | 204906..206690 (+) | 1785 | WP_009880874.1 | ABC transporter ATP-binding protein | - |
| VB13_RS01145 (VB13_01195) | - | 206808..207575 (+) | 768 | WP_011054158.1 | epoxyqueuosine reductase QueH | - |
| VB13_RS01150 (VB13_01200) | - | 207685..208131 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| VB13_RS01155 (VB13_01205) | radA | 208212..209573 (+) | 1362 | WP_002986109.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49386.68 Da Isoelectric Point: 6.0962
>NTDB_id=582220 VB13_RS01155 WP_002986109.1 208212..209573(+) (radA) [Streptococcus pyogenes strain M49 591]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=582220 VB13_RS01155 WP_002986109.1 208212..209573(+) (radA) [Streptococcus pyogenes strain M49 591]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |