Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MUK78_RS00180 Genome accession   NZ_CP095088
Coordinates   33144..33734 (+) Length   196 a.a.
NCBI ID   WP_077478213.1    Uniprot ID   -
Organism   Escherichia coli isolate w264     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28144..38734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUK78_RS00145 (MUK78_00145) emrD 28626..29810 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  MUK78_RS00150 (MUK78_00150) ysdE 29892..29966 (+) 75 WP_211180519.1 protein YsdE -
  MUK78_RS00155 (MUK78_00155) tisB 30229..30318 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  MUK78_RS00160 (MUK78_00160) - 30606..30896 (-) 291 WP_000454297.1 hypothetical protein -
  MUK78_RS00165 (MUK78_00165) ivbL 30883..30981 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  MUK78_RS00170 (MUK78_00170) ilvB 31087..32775 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  MUK78_RS00175 (MUK78_00175) ilvN 32779..33069 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  MUK78_RS00180 (MUK78_00180) letA 33144..33734 (+) 591 WP_077478213.1 transcriptional regulator UhpA Regulator
  MUK78_RS00185 (MUK78_00185) uhpB 33734..35236 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  MUK78_RS00190 (MUK78_00190) uhpC 35246..36565 (+) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  MUK78_RS00195 (MUK78_00195) uhpT 36703..38094 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=582065 MUK78_RS00180 WP_077478213.1 33144..33734(+) (letA) [Escherichia coli isolate w264]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGCEALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=582065 MUK78_RS00180 WP_077478213.1 33144..33734(+) (letA) [Escherichia coli isolate w264]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGTGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378