Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   SPN034183_RS09485 Genome accession   NC_021028
Coordinates   1756330..1757367 (-) Length   345 a.a.
NCBI ID   WP_000727279.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN034183     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1751330..1762367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN034183_RS09465 (SPN034183_17260) - 1752069..1753400 (-) 1332 WP_000390039.1 hemolysin family protein -
  SPN034183_RS09470 (SPN034183_17270) endA 1753691..1754515 (-) 825 WP_001036786.1 DNA-entry nuclease EndA Machinery gene
  SPN034183_RS09475 (SPN034183_17280) - 1754554..1754742 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  SPN034183_RS09480 (SPN034183_17290) murA 1754735..1756018 (-) 1284 WP_000358034.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SPN034183_RS11995 (SPN034183_17300) - 1756042..1756272 (-) 231 WP_001809307.1 DUF1146 family protein -
  SPN034183_RS09485 (SPN034183_17310) sepM 1756330..1757367 (-) 1038 WP_000727279.1 SepM family pheromone-processing serine protease Regulator
  SPN034183_RS09490 (SPN034183_17320) coaD 1757351..1757839 (-) 489 WP_001280736.1 pantetheine-phosphate adenylyltransferase -
  SPN034183_RS09495 (SPN034183_17330) rsmD 1757829..1758368 (-) 540 WP_000706951.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SPN034183_RS09500 (SPN034183_17340) asnA 1758433..1759425 (-) 993 WP_000747993.1 aspartate--ammonia ligase -
  SPN034183_RS09510 (SPN034183_17350) - 1759537..1760220 (-) 684 WP_015545711.1 Bax inhibitor-1/YccA family protein -
  SPN034183_RS09515 (SPN034183_17360) - 1760276..1761015 (-) 740 Protein_1805 RNA methyltransferase -
  SPN034183_RS09520 (SPN034183_17370) - 1761049..1761327 (+) 279 WP_001174613.1 acylphosphatase -
  SPN034183_RS09525 (SPN034183_17380) yidC 1761405..1762331 (+) 927 WP_000835949.1 membrane protein insertase YidC -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37565.63 Da        Isoelectric Point: 5.0724

>NTDB_id=58198 SPN034183_RS09485 WP_000727279.1 1756330..1757367(-) (sepM) [Streptococcus pneumoniae SPN034183]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=58198 SPN034183_RS09485 WP_000727279.1 1756330..1757367(-) (sepM) [Streptococcus pneumoniae SPN034183]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(130-193)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(231-298)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

59.357

99.13

0.588

Multiple sequence alignment