Detailed information NTG0580723

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: MTX62_RS04305
• Genome accession: NZ_CP094853
• Coordinates: 874202..877048 (+)
• Length: 948 a.a.
• NCBI ID: WP_000662681.1
• Uniprot ID: Q8NXL9
• Organism: Staphylococcus aureus strain NY2010
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 869202..882048

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MTX62_RS04280 (MTX62_04280)	-	869789..869896 (+)	108	WP_001790093.1	hypothetical protein	-
MTX62_RS04285 (MTX62_04285)	-	870044..870883 (+)	840	WP_000749380.1	CHAP domain-containing protein	-
MTX62_RS04290 (MTX62_04290)	-	871057..871707 (+)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
MTX62_RS04295 (MTX62_04295)	-	871704..871940 (+)	237	WP_000638419.1	CsbA family protein	-
MTX62_RS04300 (MTX62_04300)	uvrB	872209..874194 (+)	1986	WP_000229253.1	excinuclease ABC subunit UvrB	Machinery gene
MTX62_RS04305 (MTX62_04305)	uvrA	874202..877048 (+)	2847	WP_000662681.1	excinuclease ABC subunit UvrA	Machinery gene
MTX62_RS04310 (MTX62_04310)	hprK	877710..878642 (+)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
MTX62_RS04315 (MTX62_04315)	lgt	878648..879487 (+)	840	WP_000513308.1	prolipoprotein diacylglyceryl transferase	-
MTX62_RS04320 (MTX62_04320)	-	879495..879980 (+)	486	WP_001224793.1	DapH/DapD/GlmU-related protein	-
MTX62_RS04325 (MTX62_04325)	-	879988..881427 (+)	1440	WP_000057549.1	tetratricopeptide repeat protein	-

Sequence

Protein

• Length: 948 a.a.
• Molecular weight: 105368.12 Da
• Isoelectric Point: 6.2757

>NTDB_id=580723 MTX62_RS04305 WP_000662681.1 874202..877048(+) (uvrA) [Staphylococcus aureus strain NY2010]
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG
LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR
KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID
GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL
LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY
MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL
NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI
GPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGV
SGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK
IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN
IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG
DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK

Nucleotide

• Length: 2847 bp

>NTDB_id=580723 MTX62_RS04305 WP_000662681.1 874202..877048(+) (uvrA) [Staphylococcus aureus strain NY2010]
ATGAAAGAACCATCCATAGTAGTAAAAGGTGCTCGTGCGCATAACTTGAAAGATATTGATATCGAACTACCTAAAAATAA
ATTAATTGTTATGACAGGTTTATCTGGGTCAGGTAAATCGTCATTAGCATTCGATACTATATATGCTGAAGGACAACGAC
GTTATGTTGAATCATTAAGTGCCTATGCGCGTCAATTTTTAGGCCAAATGGACAAACCAGATGTTGATACAATTGAAGGA
TTATCGCCAGCAATTTCAATAGATCAAAAAACAACAAGTAAAAATCCAAGATCAACTGTAGCAACAGTAACAGAAATATA
TGATTATATACGTTTGTTATATGCACGTGTTGGTAAACCTTACTGTCCAAATCACAATATAGAAATTGAATCGCAAACAG
TACAACAAATGGTTGACCGCATTATGGAATTAGAGGCACGTACAAAGATTCAATTATTAGCACCTGTCATCGCTCATCGT
AAAGGTAGTCATGAAAAGCTAATCGAAGATATTGGTAAAAAAGGTTATGTACGTTTAAGAATCGATGGCGAAATTGTTGA
TGTAAATGATGTACCTACTTTAGATAAGAACAAGAATCATACAATAGAAGTTGTTGTAGACCGATTAGTTGTTAAAGATG
GAATTGAAACACGACTAGCTGACTCTATAGAAACTGCCTTAGAGCTTTCAGAAGGACAATTAACAGTCGATGTCATTGAC
GGGGAAGACCTTAAGTTTTCAGAAAGCCATGCTTGTCCTATATGTGGATTTTCAATCGGAGAGTTAGAACCAAGAATGTT
TAGCTTTAACAGTCCTTTTGGTGCTTGTCCGACATGTGATGGCTTAGGCCAAAAGTTAACAGTCGATGTAGACTTGGTTG
TTCCCGACAAAGATAAGACGCTAAACGAAGGTGCAATAGAACCTTGGATACCGACGAGTTCTGATTTTTATCCAACATTG
TTAAAACGTGTTTGTGAAGTTTATAAAATCAATATGGATAAACCTTTTAAAAAGTTAACAGAACGTCAACGTGATATTTT
ATTGTATGGTTCTGGTGACAAAGAAATTGAATTTACATTTACACAACGTCAAGGTGGTACTAGAAAACGAACAATGGTTT
TCGAGGGTGTAGTTCCTAATATAAGTAGACGATTCCATGAATCTCCTTCAGAATATACACGTGAAATGATGAGTAAATAT
ATGACTGAACTACCTTGCGAAACTTGTCATGGAAAGCGATTGAGTCGTGAAGCGTTATCTGTTTATGTAGGTGGTTTAAA
TATTGGTGAAGTAGTCGAATATTCAATCAGTCAAGCGCTGAACTATTATAAAAACATTGATTTGTCAGAACAAGATCAAG
CGATTGCAAATCAAATATTGAAAGAAATTATTTCCCGACTCACTTTTTTAAATAATGTGGGACTTGAATATTTAACGTTA
AACAGAGCTTCAGGTACACTTTCAGGTGGTGAAGCACAACGTATTCGATTAGCAACGCAAATTGGGTCGCGTTTGACTGG
TGTCTTATATGTATTAGATGAGCCATCAATTGGACTGCATCAAAGAGATAATGATCGATTAATTAATACACTTAAAGAAA
TGAGAGATTTAGGAAATACTTTAATTGTAGTTGAACACGATGATGATACAATGCGTGCGGCTGATTACTTAGTGGATATA
GGTCCTGGTGCTGGTGAACATGGAGGGCAGATTGTGTCTAGTGGTACTCCTCAAAAGGTAATGAAAGATAAAAAATCATT
AACAGGACAATACTTGAGTGGTAAGAAACGTATTGAAGTACCTGAATATCGCAGACCGGCTTCAGATCGTAAAATTTCTA
TACGTGGAGCTAGAAGCAACAATCTTAAAGGGGTTGATGTGGACATACCACTATCAATCATGACGGTTGTTACAGGTGTA
TCAGGTTCTGGTAAAAGCTCATTAGTAAATGAAGTATTATACAAATCATTAGCTCAAAAAATTAATAAATCTAAAGTAAA
GCCAGGATTGTACGATAAGATTGAAGGTATTGATCAACTTGATAAAATTATTGATATTGATCAATCACCAATAGGTAGAA
CGCCACGCTCTAATCCAGCAACATATACTGGTGTGTTTGATGATATACGTGATGTGTTTGCGCAAACAAATGAAGCTAAA
ATTCGAGGATATCAAAAAGGGCGTTTTAGTTTTAATGTAAAAGGTGGACGCTGTGAAGCTTGTAAAGGTGACGGTATTAT
TAAAATTGAAATGCATTTTTTACCTGATGTTTATGTTCCTTGTGAAGTGTGTGATGGTAAACGATATAATCGTGAGACAC
TAGAGGTTACTTACAAAGGTAAAAATATTGCTGACATTTTAGAAATGACTGTTGAAGAAGCAACACAATTTTTTGAAAAT
ATTCCTAAGATTAAGCGCAAGTTACAAACACTAGTTGATGTTGGTCTTGGATACGTCACATTAGGTCAACAAGCTACAAC
GTTATCAGGTGGTGAGGCTCAACGTGTGAAACTTGCATCTGAACTTCATAAACGTTCAACTGGTAAATCTATTTATATCC
TAGATGAACCGACAACAGGGTTACATGTTGACGATATTAGTAGATTATTAAAAGTATTAAACCGATTAGTTGAAAATGGT
GATACTGTTGTAATTATTGAACATAACCTAGATGTTATCAAAACAGCAGACTATATTATAGACTTAGGTCCTGAAGGTGG
TAGTGGCGGTGGTACTATTGTTGCGACTGGCACACCCGAAGATATTGCTCAGACAAAGTCATCATATACAGGAAAGTATT
TAAAAGAAGTACTTGAACGAGATAAACAAAATACTGAAGATAAATAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-399)

• ABC transporter (ABC_tran) (622-858)

3D structure

• AlphaFold DB: Q8NXL9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae TIGR4	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae D39	66.773	99.051	0.661