Detailed information NTG0580513

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6L83_RS08725
• Genome accession: NZ_CP077270
• Coordinates: 1784096..1785142 (+)
• Length: 348 a.a.
• NCBI ID: WP_011275375.1
• Uniprot ID: A0A2A1K920
• Organism: Staphylococcus haemolyticus strain FDAARGOS 1453
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1779096..1790142

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L83_RS08700 (I6L83_08700)	map	1779956..1780708 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
I6L83_RS08705 (I6L83_08705)	-	1780833..1781690 (-)	858	WP_011275370.1	SDR family oxidoreductase	-
I6L83_RS08710 (I6L83_08710)	-	1781762..1782774 (-)	1013	Protein_1709	HoxN/HupN/NixA family nickel/cobalt transporter	-
I6L83_RS08715 (I6L83_08715)	-	1782987..1783373 (+)	387	WP_011275373.1	hypothetical protein	-
I6L83_RS08720 (I6L83_08720)	liaF	1783398..1784099 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
I6L83_RS08725 (I6L83_08725)	vraS	1784096..1785142 (+)	1047	WP_011275375.1	sensor histidine kinase	Regulator
I6L83_RS08730 (I6L83_08730)	vraR	1785132..1785761 (+)	630	WP_011275376.1	two-component system response regulator VraR	Regulator
I6L83_RS08735 (I6L83_08735)	-	1785825..1787036 (-)	1212	WP_011275377.1	YihY/virulence factor BrkB family protein	-
I6L83_RS08740 (I6L83_08740)	-	1787233..1787517 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
I6L83_RS08745 (I6L83_08745)	-	1787523..1787987 (-)	465	WP_011275379.1	low molecular weight protein-tyrosine-phosphatase	-
I6L83_RS08750 (I6L83_08750)	-	1788129..1788338 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
I6L83_RS08755 (I6L83_08755)	-	1788352..1789599 (+)	1248	WP_011275381.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40179.58 Da
• Isoelectric Point: 6.0550

>NTDB_id=580513 I6L83_RS08725 WP_011275375.1 1784096..1785142(+) (vraS) [Staphylococcus haemolyticus strain FDAARGOS 1453]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIENERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=580513 I6L83_RS08725 WP_011275375.1 1784096..1785142(+) (vraS) [Staphylococcus haemolyticus strain FDAARGOS 1453]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATTGAGCATGCCATTGAAGGAGAAACAGTAGGTATCAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATCT
TTATCAAACATTAGTTCCTCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGAATGAACGACAGAGATTAGCTCGCGAGTTACATGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCTATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAATCTCAACTTGAAATGCGCGCATTATTACTTCATTTGAGACCTTTAGGACTAAAAG
ATAAATCACTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTTCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAGG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCATTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2A1K920

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.643	99.713	0.914