Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I6L83_RS08380 Genome accession   NZ_CP077270
Coordinates   1716772..1717488 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain FDAARGOS 1453     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1711772..1722488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L83_RS08360 (I6L83_08360) - 1711814..1713058 (+) 1245 WP_053024112.1 ammonium transporter -
  I6L83_RS08365 (I6L83_08365) - 1713158..1714117 (+) 960 WP_016931061.1 LacI family DNA-binding transcriptional regulator -
  I6L83_RS08370 (I6L83_08370) - 1714202..1715686 (+) 1485 WP_057504816.1 sucrose-6-phosphate hydrolase -
  I6L83_RS08375 (I6L83_08375) - 1715690..1716655 (+) 966 WP_016931059.1 carbohydrate kinase -
  I6L83_RS08380 (I6L83_08380) agrA 1716772..1717488 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  I6L83_RS08385 (I6L83_08385) agrC 1717507..1718790 (-) 1284 WP_029376653.1 quorum-sensing sensor histidine kinase AgrC -
  I6L83_RS08390 (I6L83_08390) agrD 1718822..1718959 (-) 138 WP_011275303.1 cyclic lactone autoinducer peptide AgrD -
  I6L83_RS08395 (I6L83_08395) - 1718962..1719528 (-) 567 WP_011275304.1 accessory gene regulator AgrB -
  I6L83_RS08400 (I6L83_08400) - 1720258..1721043 (-) 786 WP_011275305.1 carbon-nitrogen family hydrolase -
  I6L83_RS08405 (I6L83_08405) - 1721236..1721859 (-) 624 WP_011275306.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=580512 I6L83_RS08380 WP_011275301.1 1716772..1717488(-) (agrA) [Staphylococcus haemolyticus strain FDAARGOS 1453]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=580512 I6L83_RS08380 WP_011275301.1 1716772..1717488(-) (agrA) [Staphylococcus haemolyticus strain FDAARGOS 1453]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCA
ATTGGGAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCGATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACATACCCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAGACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGGTTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAATAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCCGTTCGTAATGTAAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878