Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   I6L86_RS08460 Genome accession   NZ_CP077259
Coordinates   1772660..1773469 (-) Length   269 a.a.
NCBI ID   WP_000004960.1    Uniprot ID   F9HDX9
Organism   Streptococcus mitis strain FDAARGOS 1456     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1767660..1778469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L86_RS08435 (I6L86_08435) - 1769136..1770854 (+) 1719 WP_000121686.1 phospho-sugar mutase -
  I6L86_RS08440 (I6L86_08440) - 1770966..1771313 (+) 348 WP_000434630.1 thiol reductase thioredoxin -
  I6L86_RS08445 (I6L86_08445) - 1771351..1772028 (-) 678 WP_000566125.1 potassium channel family protein -
  I6L86_RS08450 (I6L86_08450) - 1772071..1772325 (-) 255 WP_004239453.1 type II toxin-antitoxin system RelE family toxin -
  I6L86_RS08455 (I6L86_08455) relB 1772327..1772569 (-) 243 WP_000208079.1 type II toxin-antitoxin system RelB family antitoxin -
  I6L86_RS08460 (I6L86_08460) vicX 1772660..1773469 (-) 810 WP_000004960.1 MBL fold metallo-hydrolase Regulator
  I6L86_RS08465 (I6L86_08465) micB 1773462..1774820 (-) 1359 WP_000571163.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6L86_RS08470 (I6L86_08470) micA 1774813..1775520 (-) 708 WP_000722072.1 response regulator YycF Regulator
  I6L86_RS08475 (I6L86_08475) mutY 1775576..1776751 (-) 1176 WP_000886130.1 A/G-specific adenine glycosylase -
  I6L86_RS08480 (I6L86_08480) pta 1776940..1777914 (-) 975 WP_000451571.1 phosphate acetyltransferase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29914.87 Da        Isoelectric Point: 6.1738

>NTDB_id=580405 I6L86_RS08460 WP_000004960.1 1772660..1773469(-) (vicX) [Streptococcus mitis strain FDAARGOS 1456]
MSETGFKYSILASGSSGNSFYLETPKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIESNHDVEILRAGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGIDFKVYDTSPDTATPLTDI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=580405 I6L86_RS08460 WP_000004960.1 1772660..1773469(-) (vicX) [Streptococcus mitis strain FDAARGOS 1456]
ATGAGTGAAACAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCCTTTTATCTGGAAACGCCAAAAAA
GAAACTTTTAGTGGATGCAGGCTTATCTGGTAAGAAAATCACCAGCCTACTTGCTGAAATAAATCGCAAGCCAGAAGACT
TGGATGCCATTTTGATTACCCATGAGCATTCAGACCATATCCATGGAGTCGGTGTGTTGGCTCGCAAGTATGGTATGGAT
CTTTACGCCAATGAAAAGACCTGGCAGGCTATGGAAAATAGCAAGTATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
CTTTGAAATGGGCAAAACAAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGTCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGACAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTTAGTGACCGTATGGCAGGA
ATTGTCGAGAATGCAGATGGCTATCTTATCGAGTCCAACCATGATGTAGAGATTTTGCGAGCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATACTATCGGATCTGGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGTACCTTGGGAA
ACCGCACTAAGAAAATCTACCTTGGTCATTTATCTAAGGAGAACAATATCAAGGAACTGGCTCATATGACCATGGTAAAT
CAGTTGGCTCAAGCTGATCTTGGAGTTGGGATAGACTTTAAGGTATATGATACCTCACCAGATACCGCAACACCATTGAC
AGATATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9HDX9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

78.067

100

0.781