Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   I6L84_RS01500 Genome accession   NZ_CP077224
Coordinates   278129..280360 (-) Length   743 a.a.
NCBI ID   WP_060554044.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 273129..285360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS01470 (I6L84_01470) - 274532..274948 (-) 417 WP_060554050.1 MarR family winged helix-turn-helix transcriptional regulator -
  I6L84_RS01475 (I6L84_01475) - 275010..275447 (+) 438 WP_060554049.1 GNAT family N-acetyltransferase -
  I6L84_RS01480 (I6L84_01480) - 275484..275783 (-) 300 WP_060554048.1 DUF1827 family protein -
  I6L84_RS01485 (I6L84_01485) - 275891..276334 (-) 444 WP_060554047.1 NUDIX hydrolase -
  I6L84_RS01490 (I6L84_01490) - 276493..277383 (+) 891 WP_060554046.1 YafY family protein -
  I6L84_RS01495 (I6L84_01495) - 277443..278048 (+) 606 WP_060554045.1 GyrI-like domain-containing protein -
  I6L84_RS01500 (I6L84_01500) clpE 278129..280360 (-) 2232 WP_060554044.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  I6L84_RS01505 (I6L84_01505) - 280614..280844 (+) 231 WP_008809091.1 DUF1797 family protein -
  I6L84_RS01510 (I6L84_01510) - 280978..281832 (+) 855 WP_008809090.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  I6L84_RS01515 (I6L84_01515) - 281829..282602 (+) 774 WP_060554043.1 HAD hydrolase family protein -
  I6L84_RS01520 (I6L84_01520) - 282710..283552 (+) 843 WP_060554042.1 NAD(P)H-hydrate dehydratase -
  I6L84_RS01525 (I6L84_01525) xseA 283708..285048 (+) 1341 WP_060554041.1 exodeoxyribonuclease VII large subunit -
  I6L84_RS01530 (I6L84_01530) - 285026..285238 (+) 213 WP_060554040.1 exodeoxyribonuclease VII small subunit -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 82949.01 Da        Isoelectric Point: 5.0184

>NTDB_id=580001 I6L84_RS01500 WP_060554044.1 278129..280360(-) (clpE) [Streptococcus gordonii strain FDAARGOS 1454]
MLCQNCKINESTIHLYTNVNGKKQQVDLCQNCYQIMKTDPNNSLFGGLTNMNNHNMDPFDDFFNHLGNFQGPKDPTPPTQ
SGGSYGGGNYGPGSNNQRPQSASNKPKGLLEEFGINVTEIARRGDIDPVIGRDDEIRRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDSDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRNRNDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVRYTDEAIEA
AAILSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFVDPKEIDRRLIEAENLKTQATRDEDYEKAAYFRDQIAKYKEMQNA
KIDEQDTPIISEKEIEAIVEQKTNIPVGDLKEKEQSQLIHLASDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKALSKDNLLQIVDLMLEDVNNRLASNDIHLDVTTKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTDK
DLKAIMTSNGKIIIKGKQKAELD

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=580001 I6L84_RS01500 WP_060554044.1 278129..280360(-) (clpE) [Streptococcus gordonii strain FDAARGOS 1454]
ATGCTTTGCCAAAACTGTAAAATCAATGAATCTACCATTCATTTATATACTAATGTTAATGGTAAAAAACAACAAGTCGA
CCTCTGTCAAAATTGCTATCAGATTATGAAAACCGATCCAAATAACTCTCTATTTGGTGGACTGACAAATATGAATAATC
ATAACATGGATCCTTTTGATGATTTCTTTAATCATCTAGGAAATTTCCAAGGGCCGAAAGATCCGACACCTCCAACTCAG
TCAGGTGGTAGTTATGGAGGGGGCAACTATGGTCCTGGCTCTAACAACCAGCGTCCTCAGTCAGCTTCCAATAAACCAAA
AGGTCTTTTGGAAGAGTTTGGTATTAATGTTACAGAAATTGCTCGACGTGGTGATATTGATCCAGTGATTGGACGGGATG
ATGAAATTCGTCGTGTTATAGAAATTCTCAATCGCCGAACTAAGAACAATCCAGTCCTTATCGGTGAACCTGGTGTCGGA
AAGACTGCTGTTGTGGAGGGCTTGGCTCAAAAAATAGTCGACAGTGATGTGCCTCAAAAATTGCAAGGAAAAGAGGTTAT
TCGGCTTGATGTTGTCAGCCTTGTTCAGGGAACTGGTATTCGCGGGCAATTTGAAGAACGAATGCAAAAACTCATGGATG
AGATTCGCAATCGCAATGATATCATTCTCTTTATTGATGAAATCCATGAAATTGTTGGAGCTGGTTCTGCGGGCGATGGG
AACATGGATGCTGGAAATATTCTCAAACCTGCTCTTGCTCGAGGTGAACTTCAACTGGTTGGAGCTACTACTCTCAATGA
ATATCGTATCATTGAAAAAGATGCAGCTTTAGAAAGACGGATGCAACCAGTCAAAGTAGATGAACCAACCGTAGAAGAAA
CGATCACAATTCTAAAGGGTATTCAAAAGAAGTACGAAGATTACCACCATGTTCGCTACACAGATGAGGCTATTGAAGCC
GCAGCCATCCTATCTAATCGTTATATTCAGGACCGTTTCCTTCCTGATAAAGCTATCGATCTTTTGGATGAATCAGGCTC
TAAGATGAACCTAACTCTCAATTTTGTCGATCCTAAGGAAATTGATAGACGCTTGATAGAGGCTGAAAACCTTAAAACCC
AGGCCACTCGTGATGAAGATTATGAAAAGGCAGCCTACTTCCGTGACCAAATTGCCAAATATAAGGAAATGCAAAATGCT
AAAATAGATGAACAAGATACTCCTATCATCAGTGAGAAGGAGATCGAAGCTATTGTTGAGCAAAAAACAAATATTCCAGT
TGGCGATTTGAAGGAAAAAGAACAGTCTCAACTTATTCATTTAGCCAGTGATTTGAAGTCTCATGTCATTGGGCAGGATG
ATGCAGTTGATAAGATTGCAAAAGCCATCCGTCGTAATCGTGTGGGATTAGGCAGTCCAAACCGGCCAATCGGAAGTTTC
CTTTTTGTTGGACCGACAGGCGTTGGAAAAACTGAACTTTCCAAACAATTGGCCATCGAACTTTTTGGTTCTGCCGATAG
CATGATTCGTTTTGATATGAGTGAATACATGGAAAAACATAGCGTTGCCAAACTTGTGGGAGCACCTCCAGGCTACGTTG
GCTATGAAGAAGCAGGACAGTTGACTGAACGTGTTCGTCGTAATCCATACTCACTCATTCTCTTAGATGAGGTGGAAAAA
GCTCATCCAGATGTCATGCATATGTTCTTACAAGTCCTAGATGATGGACGTTTGACTGATGGTCAAGGTAGGACAGTCAG
CTTCAAAGATACCATTATTATCATGACTTCCAATGCAGGAACTGGCAAAGTGGAAGCTAGCGTTGGCTTTGGTGCTGCTC
GAGAAGGTCGGACAAATTCTGTCTTAGGTGAGTTAGGTAACTTCTTTAGTCCAGAATTCATGAATCGATTTGATGGTATC
ATTGAATTCAAGGCATTAAGCAAGGATAATCTCTTACAGATTGTGGATCTAATGCTGGAAGATGTTAATAATCGACTCGC
TAGCAACGATATTCATCTAGATGTAACAACCAAAGTCAAAGAAAAATTGGTTGATCTGGGCTACGATCCTAAGATGGGGG
CACGACCACTCCGTAGAACTATTCAGGATTATATCGAAGATGCTATTACGGACTACTACCTAGAACATCCGACAGATAAG
GATTTAAAAGCAATTATGACTAGCAATGGCAAGATTATAATTAAGGGTAAACAAAAAGCTGAGCTTGATTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA lid domain (AAA_lid_9)

(290-387)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-718)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.997

100

0.873
  clpE Streptococcus pneumoniae D39

86.997

100

0.873
  clpE Streptococcus pneumoniae R6

86.997

100

0.873
  clpE Streptococcus pneumoniae TIGR4

86.863

100

0.872
  clpE Streptococcus mutans UA159

84.853

100

0.852
  clpC Lactococcus lactis subsp. cremoris KW2

78.408

99.731

0.782
  clpC Bacillus subtilis subsp. subtilis str. 168

50.592

90.983

0.46
  clpC Streptococcus pneumoniae Rx1

47.68

84.118

0.401
  clpC Streptococcus pneumoniae D39

47.68

84.118

0.401
  clpC Streptococcus mutans UA159

46.562

86.137

0.401
  clpC Streptococcus pneumoniae TIGR4

47.52

84.118

0.4
  clpC Streptococcus thermophilus LMD-9

44.985

88.56

0.398
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.761

85.195

0.398
  clpC Streptococcus thermophilus LMG 18311

44.681

88.56

0.396