Detailed information NTG0579736

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: MUA79_RS04320
• Genome accession: NZ_CP094785
• Coordinates: 875177..878023 (+)
• Length: 948 a.a.
• NCBI ID: WP_000662687.1
• Uniprot ID: Q6GIN2
• Organism: Staphylococcus aureus strain IVB6169
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 870177..883023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA79_RS04300 (MUA79_04295)	-	871019..871858 (+)	840	WP_045178691.1	CHAP domain-containing protein	-
MUA79_RS04305 (MUA79_04300)	-	872032..872682 (+)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
MUA79_RS04310 (MUA79_04305)	-	872679..872915 (+)	237	WP_000638419.1	CsbA family protein	-
MUA79_RS04315 (MUA79_04310)	uvrB	873184..875169 (+)	1986	WP_000229253.1	excinuclease ABC subunit UvrB	Machinery gene
MUA79_RS04320 (MUA79_04315)	uvrA	875177..878023 (+)	2847	WP_000662687.1	excinuclease ABC subunit UvrA	Machinery gene
MUA79_RS04325 (MUA79_04320)	hprK	878634..879566 (+)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
MUA79_RS04330 (MUA79_04325)	lgt	879572..880414 (+)	843	WP_000508984.1	prolipoprotein diacylglyceryl transferase	-
MUA79_RS04335 (MUA79_04330)	-	880422..880907 (+)	486	WP_001224791.1	acyltransferase	-
MUA79_RS04340 (MUA79_04335)	-	880915..882354 (+)	1440	WP_045178695.1	tetratricopeptide repeat protein	-

Sequence

Protein

• Length: 948 a.a.
• Molecular weight: 105367.13 Da
• Isoelectric Point: 6.3740

>NTDB_id=579736 MUA79_RS04320 WP_000662687.1 875177..878023(+) (uvrA) [Staphylococcus aureus strain IVB6169]
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG
LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR
KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID
GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL
LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY
MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL
NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI
GPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGV
SGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK
IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN
IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG
DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK

Nucleotide

• Length: 2847 bp

>NTDB_id=579736 MUA79_RS04320 WP_000662687.1 875177..878023(+) (uvrA) [Staphylococcus aureus strain IVB6169]
ATGAAAGAACCATCCATAGTAGTAAAAGGTGCTCGTGCGCATAACTTGAAAGATATTGATATCGAACTACCTAAAAATAA
ATTAATTGTTATGACAGGATTATCTGGGTCAGGTAAATCGTCATTAGCATTCGATACTATATATGCTGAAGGACAACGAC
GTTATGTTGAATCATTAAGTGCCTATGCGCGTCAATTTTTAGGGCAAATGGACAAACCAGATGTTGATACTATTGAAGGA
TTATCGCCAGCAATTTCAATAGATCAAAAAACAACAAGTAAAAATCCAAGGTCAACTGTTGCAACAGTAACAGAAATATA
TGATTATATACGTTTGTTATATGCACGTGTTGGTAAACCTTACTGTCCAAATCACAATATAGAAATTGAATCGCAAACAG
TACAACAAATGGTTGACCGCATTATGGAATTAGAGGCACGTACAAAGATTCAATTATTAGCACCTGTCATCGCTCATCGT
AAAGGTAGTCATGAAAAGCTAATCGAAGATATTGGTAAAAAAGGTTATGTACGTTTAAGAATCGATGGCGAAATTGTTGA
TGTAAATGATGTACCTACATTAGATAAGAACAAGAATCATACAATAGAAGTTGTTGTAGACCGATTAGTTGTTAAAGATG
GAATTGAAACACGACTAGCTGACTCTATAGAAACTGCGTTAGAGCTTTCAGAAGGACAATTAACAGTCGATGTCATTGAC
GGGGAAGACCTTAAGTTTTCAGAAAGCCACGCTTGTCCTATATGTGGATTTTCAATCGGAGAATTAGAACCAAGAATGTT
TAGCTTTAACAGTCCTTTTGGTGCTTGTCCAACATGTGATGGCTTAGGTCAAAAGTTAACAGTCGATGTAGACTTGGTTG
TTCCCGACAAAGATAAGACGCTAAACGAAGGTGCAATAGAACCATGGATACCGACGAGTTCTGATTTTTATCCAACATTG
TTAAAACGTGTTTGTGAAGTTTATAAAATCAATATGGATAAACCTTTTAAAAAGTTAACAGAACGTCAACGTGATATTTT
ATTGTATGGTTCGGGTGACAAAGAAATTGAATTTACATTTACACAACGTCAGGGTGGTACTAGAAAACGAACAATGGTTT
TCGAGGGTGTAGTTCCTAATATAAGTAGACGATTCCATGAATCTCCTTCAGAATATACACGTGAAATGATGAGTAAATAT
ATGACTGAACTACCTTGCGAAACTTGTCATGGAAAGCGATTGAGTCGTGAAGCGTTATCTGTTTATGTAGGTGGTTTAAA
TATTGGTGAAGTAGTCGAATACTCAATTAGTCAAGCGCTGAACTATTATAAAAACATTAATTTGTCAGAACAAGATCAAG
CGATTGCAAATCAAATATTGAAAGAAATTATTTCCCGACTCACTTTTTTAAATAATGTGGGACTTGAATATTTAACGCTA
AACAGAGCTTCAGGTACACTTTCAGGTGGTGAAGCACAACGTATTCGATTGGCAACGCAAATTGGGTCGCGTTTGACTGG
TGTCTTATATGTATTAGATGAGCCATCAATTGGACTGCATCAAAGAGATAATGATCGATTAATTAATACACTTAAAGAAA
TGAGAGATTTAGGAAATACTTTAATTGTAGTTGAACACGATGATGATACAATGCGTGCGGCTGATTACTTAGTGGACATA
GGGCCTGGTGCTGGTGAGCATGGAGGACAGATTGTGTCTAGTGGTACACCTCAAAAGGTAATGAAAGATAAAAAATCTTT
AACAGGACAATACTTGAGTGGTAAGAAACGTATTGAAGTACCTGAATATCGCAGACCGGCTTCAGATCGTAAAATTTCTA
TACGTGGAGCTAGAAGTAACAACCTTAAAGGGGTTGATGTGGACATACCACTTTCAATCATGACGGTCGTTACAGGTGTA
TCAGGTTCTGGTAAAAGCTCATTAGTAAATGAAGTATTATACAAATCATTAGCTCAAAAAATCAATAAATCTAAAGTAAA
GCCAGGATTGTACGATAAAATTGAAGGTATTGATCAACTTGATAAAATTATTGATATTGATCAATCACCGATAGGTAGAA
CGCCACGCTCTAATCCAGCAACATATACTGGCGTGTTTGATGATATACGTGATGTGTTTGCGCAAACAAATGAAGCTAAA
ATTCGAGGATATCAAAAAGGTCGTTTTAGTTTTAATGTAAAAGGTGGACGCTGTGAAGCTTGTAAAGGTGACGGTATTAT
TAAAATTGAAATGCATTTTTTACCTGATGTTTATGTTCCTTGTGAAGTGTGTGATGGTAAACGATATAATCGCGAGACAC
TAGAGGTTACTTACAAAGGTAAAAATATTGCTGACATTTTAGAAATGACTGTTGAAGAAGCAACACAATTTTTTGAAAAT
ATTCCTAAGATTAAGCGCAAGCTACAAACACTAGTTGATGTTGGTCTTGGATACGTCACATTAGGTCAACAAGCTACAAC
ATTATCAGGTGGTGAGGCTCAACGTGTGAAACTTGCATCTGAACTTCATAAACGTTCAACTGGTAAATCTATTTATATCC
TAGACGAACCGACAACAGGGTTACATGTTGACGATATTAGTAGATTATTAAAAGTATTAAACCGATTAGTTGAAAATGGT
GACACTGTTGTAATTATTGAACATAACCTAGATGTTATCAAAACAGCAGACTATATTATAGACTTAGGTCCTGAAGGTGG
TAGTGGCGGTGGTACTATTGTTGCGACTGGAACACCCGAAGATATTGCTCAGACAAAGTCATCATATACAGGAAAGTATT
TAAAAGAAGTACTTGAACGAGATAAACAAAATACTGAAGATAAATAA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (622-858)

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-399)

3D structure

• AlphaFold DB: Q6GIN2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae TIGR4	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae D39	66.773	99.051	0.661