Detailed information NTG0579715

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: MUA59_RS13005
• Genome accession: NZ_CP094782
• Coordinates: 2588235..2590343 (+)
• Length: 702 a.a.
• NCBI ID: WP_262607723.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain IVB6172
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2583235..2595343

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA59_RS12980 (MUA59_12945)	-	2583300..2583518 (+)	219	WP_000011686.1	sterile alpha motif-like domain-containing protein	-
MUA59_RS12985 (MUA59_12950)	-	2583908..2584339 (+)	432	WP_000455861.1	CHAP domain-containing protein	-
MUA59_RS12990 (MUA59_12955)	-	2584479..2585759 (-)	1281	WP_001191008.1	hydroxymethylglutaryl-CoA reductase, degradative	-
MUA59_RS12995 (MUA59_12960)	-	2586014..2587180 (+)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
MUA59_RS13000 (MUA59_12965)	-	2587351..2587872 (-)	522	WP_262613814.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
MUA59_RS13005 (MUA59_12970)	clpE	2588235..2590343 (+)	2109	WP_262607723.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
MUA59_RS13010 (MUA59_12975)	-	2590410..2590580 (-)	171	WP_000111115.1	FeoB-associated Cys-rich membrane protein	-
MUA59_RS13015 (MUA59_12980)	feoB	2590593..2592587 (-)	1995	WP_262613816.1	ferrous iron transport protein B	-
MUA59_RS13020 (MUA59_12985)	-	2592599..2592826 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78124.67 Da
• Isoelectric Point: 4.6911

>NTDB_id=579715 MUA59_RS13005 WP_262607723.1 2588235..2590343(+) (clpE) [Staphylococcus aureus strain IVB6172]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSTQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSARDTVEILKGIREKFEAHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMSV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=579715 MUA59_RS13005 WP_262607723.1 2588235..2590343(+) (clpE) [Staphylococcus aureus strain IVB6172]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTGCGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTACGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
CTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGATGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACAACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAGAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAGCACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACTGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTAGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAGTGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGCATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ACGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA lid domain (AAA_lid_9) (265-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.745	91.595	0.437
clpC	Lactococcus lactis subsp. cremoris KW2	45.03	94.587	0.426
clpE	Streptococcus pneumoniae Rx1	47.326	87.892	0.416
clpE	Streptococcus pneumoniae D39	47.326	87.892	0.416
clpE	Streptococcus pneumoniae R6	47.326	87.892	0.416
clpE	Streptococcus pneumoniae TIGR4	47.326	87.892	0.416
clpC	Bacillus subtilis subsp. subtilis str. 168	44.19	93.162	0.412
clpC	Streptococcus thermophilus LMD-9	44.8	89.031	0.399
clpC	Streptococcus thermophilus LMG 18311	44.64	89.031	0.397
clpC	Streptococcus pneumoniae TIGR4	43.61	89.174	0.389
clpC	Streptococcus pneumoniae Rx1	43.78	88.177	0.386
clpC	Streptococcus pneumoniae D39	43.78	88.177	0.386
clpC	Streptococcus mutans UA159	43.74	87.607	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.215	88.746	0.375