Detailed information NTG0579269

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KSF82_RS14225
• Genome accession: NZ_CP077098
• Coordinates: 2801644..2802531 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain RGB-095930
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2796644..2807531

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KSF82_RS14195 (KSF82_14185)	-	2796653..2796745 (+)	93	WP_031774855.1	hypothetical protein	-
KSF82_RS14200 (KSF82_14190)	-	2796853..2797350 (-)	498	WP_001065267.1	glutathione peroxidase	-
KSF82_RS14205 (KSF82_14195)	-	2797360..2797620 (-)	261	WP_089535315.1	hypothetical protein	-
KSF82_RS14210 (KSF82_14200)	-	2798002..2798115 (-)	114	WP_014937089.1	hypothetical protein	-
KSF82_RS14215 (KSF82_14205)	-	2798784..2800784 (-)	2001	WP_000776741.1	ABC transporter permease	-
KSF82_RS14220 (KSF82_14210)	-	2800781..2801536 (-)	756	WP_072460436.1	ABC transporter ATP-binding protein	-
KSF82_RS14225 (KSF82_14215)	braS	2801644..2802531 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KSF82_RS14230 (KSF82_14220)	braR	2802542..2803207 (-)	666	WP_089535316.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KSF82_RS14235 (KSF82_14225)	-	2803233..2803433 (-)	201	WP_070974005.1	hypothetical protein	-
KSF82_RS14240 (KSF82_14230)	-	2803631..2805055 (+)	1425	WP_072460435.1	alkaline phosphatase	-
KSF82_RS14910	-	2805115..2805216 (-)	102	WP_000731972.1	SE2200 family small protein	-
KSF82_RS14250 (KSF82_14240)	-	2805338..2805793 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KSF82_RS14255 (KSF82_14245)	-	2806037..2806798 (-)	762	WP_089535317.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=579269 KSF82_RS14225 WP_000143420.1 2801644..2802531(-) (braS) [Staphylococcus aureus strain RGB-095930]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=579269 KSF82_RS14225 WP_000143420.1 2801644..2802531(-) (braS) [Staphylococcus aureus strain RGB-095930]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993