Detailed information NTG0057914

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SPN032672_RS14175
• Genome accession: NC_021003
• Coordinates: 1661714..1662301 (-)
• Length: 195 a.a.
• NCBI ID: WP_000205166.1
• Uniprot ID: Q9ETN5
• Organism: Streptococcus pneumoniae SPN032672
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1656714..1667301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN032672_RS08825	-	1657164..1658504 (+)	1341	WP_001099892.1	sensor histidine kinase	-
SPN032672_RS08830	blpC	1658548..1658703 (-)	156	WP_000358811.1	quorum-sensing system pheromone BlpC	-
SPN032672_RS08835	-	1658760..1660121 (-)	1362	WP_001069071.1	bacteriocin secretion accessory protein	-
SPN032672_RS08840	comA/nlmT	1660132..1661622 (-)	1491	WP_001818755.1	peptide cleavage/export ABC transporter	Regulator
SPN032672_RS14175	comA/nlmT	1661714..1662301 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
SPN032672_RS08850	blpI	1662583..1662780 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
SPN032672_RS08855	blpJ	1663247..1663516 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
SPN032672_RS08860	blpU	1663585..1663815 (+)	231	WP_000379964.1	bacteriocin-like peptide BlpU	-
SPN032672_RS08865	-	1663818..1663937 (+)	120	WP_001844187.1	PncF family bacteriocin immunity protein	-
SPN032672_RS12325	-	1664236..1664400 (+)	165	WP_000727118.1	hypothetical protein	-
SPN032672_RS08875	-	1664397..1664792 (+)	396	WP_000846569.1	hypothetical protein	-
SPN032672_RS12985	-	1664806..1665620 (-)	815	Protein_1665	IS5-like element IS1515 family transposase	-
SPN032672_RS12330	-	1665877..1666681 (+)	805	WP_128887636.1	IS5 family transposase	-
SPN032672_RS08900	blpM	1666831..1667085 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22270.71 Da
• Isoelectric Point: 9.6188

>NTDB_id=57914 SPN032672_RS14175 WP_000205166.1 1661714..1662301(-) (comA/nlmT) [Streptococcus pneumoniae SPN032672]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=57914 SPN032672_RS14175 WP_000205166.1 1661714..1662301(-) (comA/nlmT) [Streptococcus pneumoniae SPN032672]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: Q9ETN5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.89	93.333	0.559
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497