Detailed information NTG0579022

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: MUA94_RS01065
• Genome accession: NZ_CP094768
• Coordinates: 235436..237544 (-)
• Length: 702 a.a.
• NCBI ID: WP_262538074.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain IVB6202
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 230436..242544

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA94_RS01050 (MUA94_01050)	-	232953..233180 (+)	228	WP_000932073.1	FeoA family protein	-
MUA94_RS01055 (MUA94_01055)	feoB	233192..235186 (+)	1995	WP_262538072.1	ferrous iron transport protein B	-
MUA94_RS01060 (MUA94_01060)	-	235199..235369 (+)	171	WP_000111115.1	FeoB-associated Cys-rich membrane protein	-
MUA94_RS01065 (MUA94_01065)	clpE	235436..237544 (-)	2109	WP_262538074.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
MUA94_RS01070 (MUA94_01070)	-	237907..238428 (+)	522	WP_197840275.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
MUA94_RS01075 (MUA94_01075)	-	238599..239765 (-)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
MUA94_RS01080 (MUA94_01080)	-	240020..241300 (+)	1281	WP_001191008.1	hydroxymethylglutaryl-CoA reductase, degradative	-
MUA94_RS01085 (MUA94_01085)	-	241440..241871 (-)	432	WP_000455861.1	CHAP domain-containing protein	-
MUA94_RS01090 (MUA94_01090)	-	242261..242479 (-)	219	WP_000011686.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78154.69 Da
• Isoelectric Point: 4.6911

>NTDB_id=579022 MUA94_RS01065 WP_262538074.1 235436..237544(-) (clpE) [Staphylococcus aureus strain IVB6202]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSTQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSARDTVEILKGIREKFEAHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNSIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMSV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=579022 MUA94_RS01065 WP_262538074.1 235436..237544(-) (clpE) [Staphylococcus aureus strain IVB6202]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTGCGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTACGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
CTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGATGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACAACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAGAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAGCACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACTGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGCTTCAATAGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTAGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAGTGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGCATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ACGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA lid domain (AAA_lid_9) (265-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-604)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.589	91.595	0.436
clpC	Lactococcus lactis subsp. cremoris KW2	44.88	94.587	0.425
clpE	Streptococcus pneumoniae Rx1	47.164	87.892	0.415
clpE	Streptococcus pneumoniae D39	47.164	87.892	0.415
clpE	Streptococcus pneumoniae R6	47.164	87.892	0.415
clpE	Streptococcus pneumoniae TIGR4	47.164	87.892	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	44.19	93.162	0.412
clpC	Streptococcus thermophilus LMD-9	44.8	89.031	0.399
clpC	Streptococcus thermophilus LMG 18311	44.64	89.031	0.397
clpC	Streptococcus pneumoniae TIGR4	43.61	89.174	0.389
clpC	Streptococcus pneumoniae Rx1	43.78	88.177	0.386
clpC	Streptococcus pneumoniae D39	43.78	88.177	0.386
clpC	Streptococcus mutans UA159	43.74	87.607	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.215	88.746	0.375