Detailed information NTG0578945

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: MUA45_RS04210
• Genome accession: NZ_CP094765
• Coordinates: 860373..863219 (+)
• Length: 948 a.a.
• NCBI ID: WP_000662687.1
• Uniprot ID: Q6GIN2
• Organism: Staphylococcus aureus strain IVB6215
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 855373..868219

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA45_RS04190 (MUA45_04185)	-	856215..857054 (+)	840	WP_000749385.1	CHAP domain-containing protein	-
MUA45_RS04195 (MUA45_04190)	-	857228..857878 (+)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
MUA45_RS04200 (MUA45_04195)	-	857875..858111 (+)	237	WP_000638419.1	CsbA family protein	-
MUA45_RS04205 (MUA45_04200)	uvrB	858380..860365 (+)	1986	WP_250396267.1	excinuclease ABC subunit UvrB	Machinery gene
MUA45_RS04210 (MUA45_04205)	uvrA	860373..863219 (+)	2847	WP_000662687.1	excinuclease ABC subunit UvrA	Machinery gene
MUA45_RS04215 (MUA45_04210)	hprK	863830..864762 (+)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
MUA45_RS04220 (MUA45_04215)	lgt	864768..865610 (+)	843	WP_000508984.1	prolipoprotein diacylglyceryl transferase	-
MUA45_RS04225 (MUA45_04220)	-	865618..866103 (+)	486	WP_001224791.1	acyltransferase	-
MUA45_RS04230 (MUA45_04225)	-	866111..867550 (+)	1440	WP_045178695.1	tetratricopeptide repeat protein	-

Sequence

Protein

• Length: 948 a.a.
• Molecular weight: 105367.13 Da
• Isoelectric Point: 6.3740

>NTDB_id=578945 MUA45_RS04210 WP_000662687.1 860373..863219(+) (uvrA) [Staphylococcus aureus strain IVB6215]
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG
LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR
KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID
GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL
LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY
MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL
NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI
GPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGV
SGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK
IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN
IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG
DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK

Nucleotide

• Length: 2847 bp

>NTDB_id=578945 MUA45_RS04210 WP_000662687.1 860373..863219(+) (uvrA) [Staphylococcus aureus strain IVB6215]
ATGAAAGAACCATCCATAGTAGTAAAAGGTGCTCGTGCGCATAACTTGAAAGATATTGATATCGAACTACCTAAAAATAA
ATTAATTGTTATGACAGGATTATCTGGGTCAGGTAAATCGTCATTAGCATTCGATACTATATATGCTGAAGGACAACGAC
GTTATGTTGAATCATTAAGTGCCTATGCGCGTCAATTTTTAGGGCAAATGGACAAACCAGATGTTGATACTATTGAAGGA
TTATCGCCAGCAATTTCAATAGATCAAAAAACAACAAGTAAAAATCCAAGGTCAACTGTTGCAACAGTAACAGAAATATA
TGATTATATACGTTTGTTATATGCACGTGTTGGTAAACCTTACTGTCCAAATCACAATATAGAAATTGAATCGCAAACAG
TACAACAAATGGTTGACCGCATTATGGAATTAGAGGCACGTACAAAGATTCAATTATTAGCACCTGTCATCGCTCATCGT
AAAGGTAGTCATGAAAAGCTAATCGAAGATATTGGTAAAAAAGGTTATGTACGTTTAAGAATCGATGGCGAAATTGTTGA
TGTAAATGATGTACCTACATTAGATAAGAACAAGAATCATACAATAGAAGTTGTTGTAGACCGATTAGTTGTTAAAGATG
GAATTGAAACACGACTAGCTGACTCTATAGAAACTGCGTTAGAGCTTTCAGAAGGACAATTAACAGTCGATGTCATTGAC
GGGGAAGACCTTAAGTTTTCAGAAAGCCACGCTTGTCCTATATGTGGATTTTCAATCGGAGAATTAGAACCAAGAATGTT
TAGCTTTAACAGTCCTTTTGGTGCTTGTCCAACATGTGATGGCTTAGGTCAAAAGTTAACAGTCGATGTAGACTTGGTTG
TTCCCGACAAAGATAAGACGCTAAACGAAGGTGCAATAGAACCATGGATACCGACGAGTTCTGATTTTTATCCAACATTG
TTAAAACGTGTTTGTGAAGTTTATAAAATCAATATGGATAAACCTTTTAAAAAGTTAACAGAACGTCAACGTGATATTTT
ATTGTATGGTTCGGGTGACAAAGAAATTGAATTTACATTTACACAACGTCAGGGTGGTACTAGAAAACGAACAATGGTTT
TCGAGGGTGTAGTTCCTAATATAAGTAGACGATTCCATGAATCTCCTTCAGAATATACACGTGAAATGATGAGTAAATAT
ATGACTGAACTACCTTGCGAAACTTGTCATGGAAAGCGATTGAGTCGTGAAGCGTTATCTGTTTATGTAGGTGGTTTAAA
TATTGGTGAAGTAGTCGAATACTCAATTAGTCAAGCACTGAACTATTATAAAAACATTAATTTGTCAGAACAAGATCAAG
CGATTGCAAATCAAATATTGAAAGAAATTATTTCCCGACTCACTTTTTTAAATAATGTGGGACTTGAATATTTAACGCTA
AACAGAGCTTCAGGTACACTTTCAGGTGGTGAAGCACAACGTATTCGATTGGCAACGCAAATTGGGTCGCGTTTGACTGG
TGTCTTATATGTATTAGATGAGCCATCAATTGGACTGCATCAAAGAGATAATGATCGATTAATTAATACACTTAAAGAAA
TGAGAGATTTAGGAAATACTTTAATTGTAGTTGAACACGATGATGATACAATGCGTGCGGCTGATTACTTAGTGGACATA
GGGCCTGGTGCTGGTGAGCATGGAGGACAGATTGTGTCTAGTGGTACACCTCAAAAGGTAATGAAAGATAAAAAATCTTT
AACAGGACAATACTTGAGTGGTAAGAAACGTATTGAAGTACCTGAATATCGCAGACCGGCTTCAGATCGTAAAATTTCTA
TACGTGGAGCTAGAAGTAACAACCTTAAAGGGGTTGATGTGGACATACCACTTTCAATCATGACGGTCGTTACAGGTGTA
TCAGGTTCTGGTAAAAGCTCATTAGTAAATGAAGTATTATACAAATCATTAGCTCAAAAAATCAATAAATCTAAAGTAAA
GCCAGGATTGTACGATAAAATTGAAGGTATTGATCAACTTGATAAAATTATTGATATTGATCAATCACCGATAGGTAGAA
CGCCACGCTCTAATCCAGCAACATATACTGGCGTGTTTGATGATATACGTGATGTGTTTGCGCAAACAAATGAAGCTAAA
ATTCGAGGATATCAAAAAGGTCGTTTTAGTTTTAATGTAAAAGGTGGACGCTGTGAAGCTTGTAAAGGTGACGGTATTAT
TAAAATTGAAATGCATTTTTTACCTGATGTTTATGTTCCTTGTGAAGTGTGTGATGGTAAACGATATAATCGCGAGACAC
TAGAGGTTACTTACAAAGGTAAAAATATTGCTGACATTTTAGAAATGACTGTTGAAGAAGCAACACAATTTTTTGAAAAT
ATTCCTAAGATTAAGCGCAAGCTACAAACACTAGTTGATGTTGGTCTTGGATACGTCACATTAGGTCAACAAGCTACAAC
ATTATCAGGTGGTGAGGCTCAACGTGTGAAACTTGCATCTGAACTTCATAAACGTTCAACTGGTAAATCTATTTATATCC
TAGACGAACCGACAACAGGGTTACATGTTGACGATATTAGTAGATTATTAAAAGTATTAAACCGATTAGTTGAAAATGGT
GACACTGTTGTAATTATTGAACATAACCTAGATGTTATCAAAACAGCAGACTATATTATAGACTTAGGTCCTGAAGGTGG
TAGTGGCGGTGGTACTATTGTTGCGACTGGAACACCCGAAGATATTGCTCAGACAAAGTCATCATATACAGGAAAGTATT
TAAAAGAAGTACTTGAACGAGATAAACAAAATACTGAAGATAAATAA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (622-858)

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-399)

3D structure

• AlphaFold DB: Q6GIN2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae TIGR4	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae D39	66.773	99.051	0.661