Detailed information NTG0578748

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: MUA32_RS13135
• Genome accession: NZ_CP094755
• Coordinates: 2621528..2623633 (+)
• Length: 701 a.a.
• NCBI ID: WP_262516039.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain IVB6242
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2616528..2628633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA32_RS13110 (MUA32_13105)	-	2616595..2616813 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
MUA32_RS13115 (MUA32_13110)	-	2617201..2617632 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
MUA32_RS13120 (MUA32_13115)	-	2617772..2619052 (-)	1281	WP_001191011.1	hydroxymethylglutaryl-CoA reductase, degradative	-
MUA32_RS13125 (MUA32_13120)	-	2619307..2620473 (+)	1167	WP_000172190.1	hydroxymethylglutaryl-CoA synthase	-
MUA32_RS13130 (MUA32_13125)	-	2620644..2621165 (-)	522	WP_000262597.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
MUA32_RS13135 (MUA32_13130)	clpE	2621528..2623633 (+)	2106	WP_262516039.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
MUA32_RS13140 (MUA32_13135)	-	2623703..2623873 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
MUA32_RS13145 (MUA32_13140)	feoB	2623886..2625880 (-)	1995	WP_000432892.1	ferrous iron transport protein B	-
MUA32_RS13150 (MUA32_13145)	-	2625892..2626119 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 78033.69 Da
• Isoelectric Point: 4.7460

>NTDB_id=578748 MUA32_RS13135 WP_262516039.1 2621528..2623633(+) (clpE) [Staphylococcus aureus strain IVB6242]
MNNNFFNNDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLFEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVTTEKRISELEHDKRKAVSAEEYKKADDIQKEIKSLQDKLENSNGEHTAVATVLDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLNHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=578748 MUA32_RS13135 WP_262516039.1 2621528..2623633(+) (clpE) [Staphylococcus aureus strain IVB6242]
ATGAATAACAATTTTTTCAATAATGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTATTTGAAGGCGTTAA
GTCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGTCCTGCTATTGATAAAGTCACGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAAAGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCTTGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGTAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTGGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACACTGAAGAAAAAGATATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTGTTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCACAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAAATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.607	92.154	0.448
clpE	Streptococcus pneumoniae TIGR4	47.735	88.16	0.421
clpE	Streptococcus pneumoniae R6	47.812	88.017	0.421
clpE	Streptococcus pneumoniae D39	47.812	88.017	0.421
clpE	Streptococcus pneumoniae Rx1	47.812	88.017	0.421
clpC	Lactococcus lactis subsp. cremoris KW2	46.656	89.586	0.418
clpC	Bacillus subtilis subsp. subtilis str. 168	44.122	93.438	0.412
clpC	Streptococcus thermophilus LMD-9	44.96	89.158	0.401
clpC	Streptococcus thermophilus LMG 18311	44.64	89.158	0.398
clpC	Streptococcus pneumoniae TIGR4	43.68	89.158	0.389
clpC	Streptococcus pneumoniae Rx1	43.68	89.158	0.389
clpC	Streptococcus pneumoniae D39	43.68	89.158	0.389
clpC	Streptococcus mutans UA159	43.831	87.874	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.468	89.016	0.378